Leukocyte migration through activated venular walls is a fundamental immune response that
is prerequisite to the entry of effector cells such as neutrophils, monocytes, and effector T …

Chemokines play crucial roles in combating microbial infection and initiating tissue repair by
recruiting neutrophils in a timely and coordinated manner. In humans, no less than seven …

Macrophages respond to chemical/metabolic and physical stimuli, but their effects cannot be
readily decoupled in vivo during pro-inflammatory activation. Here, we show that preventing …

Neutrophils are the most abundant immune cell type in the blood and constitute the first line
of defense against invading pathogens. Despite their important role in many diseases, they …

Neutrophil infiltration into inflamed and infected tissues is a fundamental process of the
innate immune response. While neutrophil interactions with the blood vessel wall have been …

G‐protein–coupled receptor (GPCR) signaling is essential for the spatiotemporal control of
leukocyte dynamics during immune responses. For efficient navigation through mammalian …

Immune cell locomotion is associated with amoeboid migration, a flexible mode of
movement, which depends on rapid cycles of actin polymerization and actomyosin …

Ischemia-reperfusion injury (IRI) is the main cause of morbidity and mortality due to graft
rejection after liver transplantation. During IRI, an intense inflammatory process occurs in the …

Migration of leukocytes is essential for the induction, maintenance, and regulation of
immune responses. On their trafficking routes, leukocytes encounter microenvironments of …

Neutrophil migration to injured and pathogen-infected tissues is a fundamental component
of innate immunity. An array of cellular and molecular events mediate this response to …