Metabolites are important biomarkers in human body fluids, conveying direct information of
cellular activities and physical conditions. Metabolite detection has long been a research …

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disorder of unknown origin and
the most common interstitial lung disease. It progresses with the recruitment of fibroblasts …

Rationale: A prevailing paradigm recognizes idiopathic pulmonary fibrosis (IPF) originating
from various alveolar epithelial cell (AEC) injuries, and there is a growing appreciation of …

Pulmonary fibrosis is a progressive and intractable lung disease with fibrotic features that
affects alveoli elasticity, which leading to higher rates of hospitalization and mortality …

Introduction Pulmonary fibrosis (PF) is characterized by an increase in collagen synthesis
and deposition of extracellular matrix. Several factors, including transforming growth factor …

There are a wide variety of microbiomes in the human body, most of which exist in the
gastrointestinal tract. Microbiomes and metabolites interact with the host to influence health …

Background Pulmonary exposure to multi-walled carbon nanotubes (MWCNTs) has been
reported to exert strong pro-inflammatory and pro-fibrotic adjuvant effects in mouse models …

Idiopathic pulmonary fibrosis (IPF) is a progressive disease with significant mortality and
morbidity. Approval of antifibrotic therapy has ameliorated disease progression, but therapy …

Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease characterized
by excessive deposition of fibrotic connective tissue in the lungs. Emerging evidence …

Background Radiation-induced lung injury (RILI) is the most common and serious
complication of chest radiotherapy. However, reported radioprotective agents usually lead to …