Re-drawing the maps for endemic mycoses

N Ashraf, RC Kubat, V Poplin, AA Adenis, DW Denning… - Mycopathologia, 2020 - Springer
Endemic mycoses such as histoplasmosis, coccidioidomycosis, blastomycosis,
paracoccidioidomycosis, and talaromycosis are well-known causes of focal and systemic …

Antifungal activity of thiosemicarbazones, bis (thiosemicarbazones), and their metal complexes

K Bajaj, RM Buchanan, CA Grapperhaus - Journal of Inorganic …, 2021 - Elsevier
Fungi are ubiquitous in nature, and typically cause little or no environmental or pathogenic
damage to their plant, animal, and human hosts. However, a small but growing number of …

[HTML][HTML] Fungal infections in humans: the silent crisis

K Kainz, MA Bauer, F Madeo… - Microbial Cell, 2020 - ncbi.nlm.nih.gov
Annually, over 150 million severe cases of fungal infections occur worldwide, resulting in
approximately 1.7 million deaths per year. Alarmingly, these numbers are continuously on …

Trichophyton indotineae sp. nov.: A New Highly Terbinafine-Resistant Anthropophilic Dermatophyte Species

R Kano, U Kimura, M Kakurai, J Hiruma, H Kamata… - Mycopathologia, 2020 - Springer
In this report, we describe the first isolation of two highly terbinafine (TRF)-resistant
Trichophyton interdigitale-like strains from a Nepali patient and an Indian patient with tinea …

A global view on fungal infections in humans and animals: opportunistic infections and microsporidioses

S Gnat, D Łagowski, A Nowakiewicz… - Journal of Applied …, 2021 - academic.oup.com
After cardiovascular diseases, infectious diseases are the second most common cause of
death worldwide. Although these infections are caused mainly by viruses or bacteria, a …

Candida and Candidiasis—Opportunism Versus Pathogenicity: A Review of the Virulence Traits

CN Ciurea, IB Kosovski, AD Mare, F Toma… - Microorganisms, 2020 - mdpi.com
One of the most important questions in microbiology nowadays, is how apparently harmless,
commensal yeasts like Candida spp. can cause a rising number of infections. The …

Multitalented synthetic antimicrobial peptides and their antibacterial, antifungal and antiviral mechanisms

T Vanzolini, M Bruschi, AC Rinaldi, M Magnani… - International Journal of …, 2022 - mdpi.com
Despite the great strides in healthcare during the last century, some challenges still
remained unanswered. The development of multi-drug resistant bacteria, the alarming …

Essential oils of Lamiaceae family plants as antifungals

TM Karpiński - Biomolecules, 2020 - mdpi.com
The incidence of fungal infections has been steadily increasing in recent years. Systemic
mycoses are characterized by the highest mortality. At the same time, the frequency of …

[HTML][HTML] Lipid systems for the delivery of amphotericin B in antifungal therapy

C Faustino, L Pinheiro - Pharmaceutics, 2020 - mdpi.com
Amphotericin B (AmB), a broad-spectrum polyene antibiotic in the clinic for more than fifty
years, remains the gold standard in the treatment of life-threatening invasive fungal …

Clinical Efficacy and Safety of a Novel Antifungal, Fosmanogepix, in Patients with Candidemia Caused by Candida auris: Results from a Phase 2 Trial

JA Vazquez, PG Pappas, K Boffard… - Antimicrobial agents …, 2023 - Am Soc Microbiol
Fosmanogepix (FMGX), a novel antifungal available in intravenous (IV) and oral
formulations, has broad-spectrum activity against pathogenic yeasts and molds, including …