[HTML][HTML] Acyclovir-loaded chitosan nanospheres from nano-emulsion templating for the topical treatment of herpesviruses infections

M Donalisio, F Leone, A Civra, R Spagnolo, O Ozer… - Pharmaceutics, 2018 - mdpi.com
Acyclovir is not a good candidate for passive permeation since its polarity and solubility limit
is partitioning into the stratum corneum. This work aims to develop a new topical formulation …

[HTML][HTML] Review of mathematical models of HSV-2 vaccination: Implications for vaccine development

IH Spicknall, KJ Looker, SL Gottlieb, HW Chesson… - Vaccine, 2019 - Elsevier
Abstract Development of a vaccine against herpes simplex virus type 2 (HSV-2), a life-long
sexually-transmitted infection (STI), would be a major step forward in improving global …

Disparities in burden of herpes simplex virus type 2 in China: systematic review, meta-analyses, and meta-regressions

Y Wang, X Yan, W Ai, Y Jia, C Fan, S Hu, Y Dai… - Frontiers in …, 2024 - frontiersin.org
Background The rising prevalence of herpes simplex type 2 (HSV-2) infection poses a
growing global public health challenge. A comprehensive understanding of its epidemiology …

Inhibition of HSV‐2 infection by pure compounds from Thymus capitatus extract in vitro

MM Toujani, M Rittà, A Civra, S Genovese… - Phytotherapy …, 2018 - Wiley Online Library
The Thymus genus is considered to be one of the largest genera within the Lamiaceae
family that includes approximately 350 species of perennial, aromatic herb, and subshrubs …

Dynamics analysis of a Zika–dengue co-infection model with dengue vaccine and antibody-dependent enhancement

L Wang, H Zhao - Physica A: Statistical Mechanics and Its Applications, 2019 - Elsevier
Mounting clinical and experimental evidence indicates that antibodies against dengue can
enhance Zika infection through the antibody-dependent enhancement (ADE) mechanism …

[HTML][HTML] Algorithmic approach for a unique definition of the next-generation matrix

F Avram, R Adenane, L Basnarkov, MD Johnston - Mathematics, 2023 - mdpi.com
The basic reproduction number R 0 is a concept which originated in population dynamics,
mathematical epidemiology, and ecology and is closely related to the mean number of …

Ficus religiosa L. bark extracts inhibit infection by herpes simplex virus type 2 in vitro

M Ghosh, A Civra, M Rittà, V Cagno, SG Mavuduru… - Archives of …, 2016 - Springer
Ficus religiosa extracts have been used in traditional Indian medicine to treat sexually
transmitted infections such as gonorrhea and genital ulcers. The aim of this study was to …

The traditional use of Vachellia nilotica for sexually transmitted diseases is substantiated by the antiviral activity of its bark extract against sexually transmitted viruses

M Donalisio, V Cagno, A Civra, D Gibellini… - Journal of …, 2018 - Elsevier
Abstract Ethnopharmacological relevance Vachellia (Acacia) nilotica and other plants of this
genus have been used in traditional medicine of Asian and African countries to treat many …

The AGMA1 poly (amidoamine) inhibits the infectivity of herpes simplex virus in cell lines, in human cervicovaginal histocultures, and in vaginally infected mice

M Donalisio, P Quaranta, F Chiuppesi, M Pistello… - Biomaterials, 2016 - Elsevier
The development of topical microbicides is a valid approach to protect the genital mucosa
from sexually transmitted infections that cannot be contained with effective vaccination, like …

Multi-host transmission dynamics of schistosomiasis and its optimal control

C Ding, Z Qiu, H Zhu - Mathematical Biosciences & Engineering, 2015 - aimsciences.org
In this paper we formulate a dynamical model to study the transmission dynamics of
schistosomiasis in humans and snails. We also incorporate bovines in the model to study …