Highlights•Thermodynamic principle provides an insight to understand permeation behavior
and the relation between skin and topical product.•Different determinants such as Log P …

Skin‐mediated drug delivery methods currently are receiving significant attention as a
promising approach for the enhanced delivery of drugs through the skin. Skin‐mediated …

Natural gums are a source of biopolymeric materials with a wide range of applications for
multiple purposes. These polysaccharides are extensively explored due to their low toxicity …

Transdermal drug delivery systems (TDDSs) have become innovative, fascinating drug
delivery methods intended for skin application to achieve systemic effects. TDDSs overcome …

Spray film-forming systems (SFFSs) provide great potential for the treatment of various types
of wounds. Such systems afford to prolong the action of active substances, to prevent cross …

Atopic dermatitis (AD) is the most common form of eczema and the most burdensome skin
disease globally, affecting nearly 223 million. A major AD predisposition is genetic …

Excessive exposure to ultraviolet radiation (UV) can induce oxidative stress through the over-
production of reactive oxygen species (ROS) on the skin. Myricetin (MYR), a natural …

The study aimed to perform a comprehensive in vitro and in vivo evaluation of a newly
developed, patent-pending, powder-to-hydrogel, film-forming polymer complex base, which …

In this work we studied nanoceria (CeO2NPs) and nanoceria modified by 5-fluorouracil
(5FU) as potential APIs. Nanoceria were synthesized by precipitation in a matrix of …

Dissolving microneedles are extensively applied in drug delivery systems to enhance
penetration into the skin. In this study, dissolving microneedles fabricated from …