The adhesive interactions of cells with their environment through the integrin family of
transmembrane receptors have key roles in regulating multiple aspects of cellular …

Anoikis is a programmed cell death occurring upon cell detachment from the correct
extracellular matrix, thus disrupting integrin ligation. It is a critical mechanism in preventing …

MicroRNAs have an important role in bone homeostasis. However, the detailed mechanism
of microRNA-mediated intercellular communication between bone cells remains elusive …

Signaling between endothelial cells, endothelial progenitor cells, and stromal cells is crucial
for the establishment and maintenance of vascular integrity and involves exosomes, among …

Emerging evidence indicates that microRNAs (miRNAs) have important roles in regulating
osteogenic differentiation and bone formation. Thus far, no study has established the …

The development and progression of melanoma have been attributed to independent or
combined genetic and epigenetic events. There has been remarkable progress in …

Cell-cell communication within the follicle involves many signaling molecules, and this
process may be mediated by secretion and uptake of exosomes that contain several …

Melanoma is one of the most aggressive and progressive skin cancers. It develops from
normal pigment-producing cells known as melanocytes, so it is important to know the …

Aberrant microRNA (miRNA) expression is a defining feature of human malignancy. Specific
miRNAs have been identified as promoters or suppressors of metastatic progression …

The great majority of cancer deaths are due to metastasis, which remains a poorly
understood pathological process. The formation of a metastasis reflects a succession of …