Fundamentals and applications of N-heterocyclic carbene functionalized gold surfaces and nanoparticles

G Kaur, RL Thimes, JP Camden… - Chemical …, 2022 - pubs.rsc.org
The discovery of N-heterocyclic carbenes (NHCs) revolutionized organometallic chemistry
due to their strong metal–ligand bonds. These strong bonds also lend enhanced stability to …

Antibiotics: a “GOLDen” promise?

CI Yeo, CHP Goh, ERT Tiekink, J Chew - Coordination Chemistry Reviews, 2024 - Elsevier
Bacterial infections pose a significant threat to public health and the global economy. The
misuse of antibiotics in the treatment of bacterial infections has led to a rapid development of …

Tumor-targeting NHC–Au (I) complex induces immunogenic cell death in hepatocellular carcinoma

Z Yang, M Bian, L Lv, X Chang, Z Wen… - Journal of Medicinal …, 2023 - ACS Publications
Immunogenic cell death (ICD) is a promising direction of cancer immunotherapy in
hepatocellular carcinoma (HCC). A series of novel NHC–Au (I) complexes derived from 4, 5 …

[HTML][HTML] Strategies for the improvement of metal-based chemotherapeutic treatments

D Cirri, F Bartoli, A Pratesi, E Baglini, E Barresi… - Biomedicines, 2021 - mdpi.com
This article provides an overview of the various research approaches we have explored in
recent years to improve metal-based agents for cancer or infection treatments. Although …

Exploring coordination preferences and biological applications of pyridyl-based organochalcogen (Se, Te) ligands

A Singh, A Kaushik, JS Dhau, R Kumar - Coordination Chemistry Reviews, 2022 - Elsevier
This review summarizes advancement in the field of pyridyl-based organochalcogen ligands
in terms of their coordination behavior and biological applications. Pyridylchalcogen …

N-Heterocyclic silylenes in coinage metal chemistry: an account of recent advances

M Ghosh, S Khan - Dalton Transactions, 2021 - pubs.rsc.org
This article intends to highlight and comprehensively summarize the recent developments in
the field of silylene–coinage metal chemistry. Recent years have witnessed exponential …

Solute-solvent interaction and adsorption studies of sulpha drug derivative: A DFT study

N Elangovan, N Arumugam, M Thirumavalavan… - Journal of Molecular …, 2024 - Elsevier
Abstract The adsorption of (E)-2-hydroxy-5-(((4-sulfamoyl phenyl) imino) methyl) benzoic
acid (5FSANI) on various metal clusters and chemical descriptors was investigated on the …

[HTML][HTML] Absorption studies on serotonin neurotransmitter with the platinum metal cluster using the gas phase and different solvents, topological and non-covalent …

CG Priya, BR Venkatraman, N Elangovan… - Chemical Physics …, 2023 - Elsevier
The absorption studies on serotonin (STO) and platinum metal clusters were investigated.
The STO-Pt3 (gas phase) cluster has the maximum adsorption energy, whereas the water …

New insights into the behavior of NHC-gold complexes in cancer cells

G Augello, A Azzolina, F Rossi, F Prencipe… - Pharmaceutics, 2023 - mdpi.com
Among the non-platinum antitumor agents, gold complexes have received increased
attention owing to their strong antiproliferative effects, which generally occur through non …

Strategies for the design of analogs of auranofin endowed with anticancer potential

V Vitali, L Massai, L Messori - Expert Opinion on Drug Discovery, 2024 - Taylor & Francis
Introduction Auranofin (AF) is a well-established, FDA-approved, antiarthritic gold drug that
is currently being reevaluated for a variety of therapeutic indications through drug …