Biomaterials for articular cartilage tissue engineering: Learning from biology

AR Armiento, MJ Stoddart, M Alini, D Eglin - Acta biomaterialia, 2018 - Elsevier
Articular cartilage is commonly described as a tissue that is made of up to 80% water, is
devoid of blood vessels, nerves, and lymphatics, and is populated by only one cell type, the …

[HTML][HTML] Harnessing knee joint resident mesenchymal stem cells in cartilage tissue engineering

X Xu, L Xu, J **a, C Wen, Y Liang, Y Zhang - Acta Biomaterialia, 2023 - Elsevier
Osteoarthritis (OA) is a widespread clinical disease characterized by cartilage degeneration
in middle-aged and elderly people. Currently, there is no effective treatment for OA apart …

Anti‐friction MSCs delivery system improves the therapy for severe osteoarthritis

X Yan, B Yang, Y Chen, Y Song, J Ye, Y Pan… - Advanced …, 2021 - Wiley Online Library
Osteoarthritis (OA) is a musculoskeletal disorder disease affecting about 500 million people
worldwide and mesenchymal sem cells (MSCs) therapy has been demonstrated as a …

Origin and function of cartilage stem/progenitor cells in osteoarthritis

Y Jiang, RS Tuan - Nature Reviews Rheumatology, 2015 - nature.com
Articular cartilage is a physiologically non-self-renewing avascular tissue with a singular cell
type, the chondrocyte, which functions as the load-bearing surface of the arthrodial joint …

[HTML][HTML] Advancements in hydrogel design for articular cartilage regeneration: A comprehensive review

F Hashemi-Afzal, H Fallahi, F Bagheri, MN Collins… - Bioactive Materials, 2025 - Elsevier
This review paper explores the cutting-edge advancements in hydrogel design for articular
cartilage regeneration (CR). Articular cartilage (AC) defects are a common occurrence …

Arthritic Microenvironment‐Dictated Fate Decisions for Stem Cells in Cartilage Repair

S He, H Deng, P Li, J Hu, Y Yang, Z Xu, S Liu… - Advanced …, 2023 - Wiley Online Library
The microenvironment and stem cell fate guidance of post‐traumatic articular cartilage
regeneration is primarily the focus of cartilage tissue engineering. In articular cartilage, stem …

Co-culture of osteochondral explants and synovial membrane as in vitro model for osteoarthritis

E Haltmayer, I Ribitsch, S Gabner, J Rosser… - PLoS …, 2019 - journals.plos.org
The purpose of the current study was to establish an in vitro model for osteoarthritis (OA) by
co-culture of osteochondral and synovial membrane explants. Osteochondral explants were …

Use of recombinant human stromal cell–derived factor 1α–loaded fibrin/hyaluronic acid hydrogel networks to achieve functional repair of full‐thickness bovine articular …

Y Yu, MJ Brouillette, D Seol, H Zheng… - Arthritis & …, 2015 - Wiley Online Library
Objective Articular cartilage damage after joint trauma seldom heals and often leads to
osteoarthritis. We previously identified a migratory chondrogenic progenitor cell (CPC) …

Pathogenesis of posttraumatic osteoarthritis of the ankle

EC Nwankwo, LA Labaran, V Athas… - Orthopedic …, 2019 - orthopedic.theclinics.com
PTOAA is most common after a traumatic injury to the ankle joint. Pathogenic mechanisms of
PTOAA are not fully understood. Metabolites, lipids, and cytokines are associated with the …

Articular cartilage regeneration and tissue engineering models: a systematic review

SG Walter, R Ossendorff, FA Schildberg - Archives of Orthopaedic and …, 2019 - Springer
Introduction Cartilage regeneration and restoration is a major topic in orthopedic research
as cartilaginous degeneration and damage is associated with osteoarthritis and joint …