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A decade's overview of 2‐aminothiophenes and their fused analogs as promising anticancer agents
DG Darwish, HAM El‐Sherief… - Archiv der …, 2024 - Wiley Online Library
Over the past decades, cancer has been a challenging domain for medicinal chemists as it
is an international health concern. In association, small molecules such as 2 …
is an international health concern. In association, small molecules such as 2 …
Biological applications of thiourea derivatives: detailed review
FA Agili - Chemistry, 2024 - mdpi.com
Thiourea and its derivatives have become a significant focal point within the organic
synthesis field, garnering attention for their diverse biological applications, including …
synthesis field, garnering attention for their diverse biological applications, including …
[HTML][HTML] Synthesis, characterization, and anticancer activity of new N, N′-Diarylthiourea derivative against breast cancer cells
The goal of the current study was to prepare two new homologous series of N, N′-
diarylurea and N, N′-diarylthiourea derivatives to investigate the therapeutic effects of …
diarylurea and N, N′-diarylthiourea derivatives to investigate the therapeutic effects of …
Electrochemical cascade sequences for remote C7–H bond thiocyanation of quinoxalin-2 (1 H)-ones with ammonium thiocyanate
R Maity, A Bankura, I Das - Green Chemistry, 2023 - pubs.rsc.org
The syntheses of C3-substituted quinoxalin-2 (1H)-one derivatives have been extensively
studied for decades, while the methods for direct functionalization at the embedded aromatic …
studied for decades, while the methods for direct functionalization at the embedded aromatic …
Design, synthesis and apoptotic activity of substituted chalcones tethered 1, 3, 5-triazine hybrids: An insights from molecular docking, molecular dynamics simulations …
A novel library of chalcone tethered 1, 3, 5-triazine hybrids (5a-j) were designed and
synthesized and their structures were confirmed by using spectroscopic/analytical …
synthesized and their structures were confirmed by using spectroscopic/analytical …
Supporting Electrolyte‐Free Electrochemical Oxidative C− H Sulfonylation and Thiocyanation of Fused Pyrimidin‐4‐Ones in an All‐Green Electrolytic System
An electrooxidative C− H functionalization is a widely accepted route to obtain sulfur‐
containing arenes and heteroarenes. However, this process often involves using non …
containing arenes and heteroarenes. However, this process often involves using non …
Ionic liquid-catalyzed, microwave-assisted green synthesis of novel Coumarin-Schiff bases: Characterization, molecular docking, biological and DFT studies
A microwave assisted green protocol for the synthesis of coumarin-linked novel Schiff base
compounds (CSB-I and CSB-II) were demonstrated by employing [TMG][OAc] ionic liquid (IL) …
compounds (CSB-I and CSB-II) were demonstrated by employing [TMG][OAc] ionic liquid (IL) …
Development of Mycobacterium tuberculosis Enoyl Acyl Reductase (InhA) Inhibitors: A Mini-Review
This review article delves into the critical role of Enoyl acyl carrier protein reductase (InhA;
ENR), a vital enzyme in the NADH-dependent acyl carrier protein reductase family …
ENR), a vital enzyme in the NADH-dependent acyl carrier protein reductase family …
5‐N, N‐Diarylaminothiazoles with Electron‐Accepting Groups: Synthesis, Photophysical Properties, and Their Application for the Detection of Hydrazine Hydrate
T Murai, N Tanaka, K Takekoshi… - European Journal of …, 2024 - Wiley Online Library
N, N‐diarylaminothiazoles containing cyano and nitro groups were synthesized using the Pd‐
catalyzed Buchwald‐Hartwig amination reaction with good yields. The cyano group in the …
catalyzed Buchwald‐Hartwig amination reaction with good yields. The cyano group in the …
Genotoxicity and Anticancer Effects of the Aminothiophene Derivatives SB-44, SB-83, and SB-200 in Cancer Cells
EDL da Silva, FA dos Santos… - Anti-Cancer Agents …, 2023 - benthamdirect.com
Introduction: Thiophene derivatives have been widely studied as promising options for the
treatment of solid tumors. Previous studies have shown that thiophene derivatives have …
treatment of solid tumors. Previous studies have shown that thiophene derivatives have …