Tools and techniques for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/COVID-19 detection
SUMMARY The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and …
respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and …
IL-6 in inflammation, autoimmunity and cancer
T Hirano - International immunology, 2021 - academic.oup.com
IL-6 is involved both in immune responses and in inflammation, hematopoiesis, bone
metabolism and embryonic development. IL-6 plays roles in chronic inflammation (closely …
metabolism and embryonic development. IL-6 plays roles in chronic inflammation (closely …
The COVID-19 pandemic: a global health crisis
CA Pollard, MP Morran… - Physiological …, 2020 - journals.physiology.org
The novel coronavirus SARS-CoV-2 was identified as the causative agent for a series of
atypical respiratory diseases in the Hubei Province of Wuhan, China in December of 2019 …
atypical respiratory diseases in the Hubei Province of Wuhan, China in December of 2019 …
SARS-CoV-2 spike protein induces inflammation via TLR2-dependent activation of the NF-κB pathway
The pathogenesis of COVID-19 is associated with a hyperinflammatory response; however,
the precise mechanism of SARS-CoV-2-induced inflammation is poorly understood. Here …
the precise mechanism of SARS-CoV-2-induced inflammation is poorly understood. Here …
Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy
H Gu, Q Chen, G Yang, L He, H Fan, YQ Deng, Y Wang… - Science, 2020 - science.org
The ongoing coronavirus disease 2019 (COVID-19) pandemic has prioritized the
development of small-animal models for severe acute respiratory syndrome coronavirus 2 …
development of small-animal models for severe acute respiratory syndrome coronavirus 2 …
Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19
ED Hottz, IG Azevedo-Quintanilha… - Blood, The Journal …, 2020 - ashpublications.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emergent pathogen
responsible for the coronavirus disease 2019 (COVID-19). Since its emergence, the novel …
responsible for the coronavirus disease 2019 (COVID-19). Since its emergence, the novel …
Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications
INTRODUCTION Many patients with coronavirus disease 2019 (COVID-19), caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, present with …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, present with …
Rapid generation of durable B cell memory to SARS-CoV-2 spike and nucleocapsid proteins in COVID-19 and convalescence
GE Hartley, ESJ Edwards, PM Aui, N Varese… - Science …, 2020 - science.org
Lasting immunity following SARS-CoV-2 infection is questioned because serum antibodies
decline in convalescence. However, functional immunity is mediated by long-lived memory T …
decline in convalescence. However, functional immunity is mediated by long-lived memory T …
A neutrophil activation signature predicts critical illness and mortality in COVID-19
Pathologic immune hyperactivation is emerging as a key feature of critical illness in COVID-
19, but the mechanisms involved remain poorly understood. We carried out proteomic …
19, but the mechanisms involved remain poorly understood. We carried out proteomic …
The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-Ι
COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has
become a global pandemic and has claimed over 2 million lives worldwide. Although the …
become a global pandemic and has claimed over 2 million lives worldwide. Although the …