The SOS response that responds to DNA damage induces many genes that are under LexA
repression. A detailed examination of LexA regulons using genome‐wide techniques has …

The presence of multiple copies of the major replicative DNA polymerase (DnaE) in some
organisms, including important pathogens and symbionts, has remained an unresolved …

Our understanding of Mycobacterium tuberculosis DNA repair mechanisms is still poor
compared with that of other bacterial organisms. However, the publication of the first …

All organisms possess a diverse set of genetic programs that are used to alter cellular
physiology in response to environmental cues. The gram-negative bacterium Escherichia …

Objectives In eubacteria, RecA is essential for recombinational DNA repair and for stalled
replication forks to resume DNA synthesis. Recent work has implicated a role for RecA in the …

In many species of bacteria most inducible DNA repair genes are regulated by LexA
homologues and are dependent on RecA for induction. We have shown previously by …

Mycobacteria exhibit two DNA damage response pathways: the LexA/RecA-dependent SOS
response and a LexA/RecA-independent pathway. Using a combination of transcriptomics …

Acinetobacter baumannii is an emerging nosocomial, opportunistic pathogen that survives
desiccation and quickly acquires resistance to multiple antibiotics. Escherichia coli gains …

The DNA damage response is crucial for bacterial survival. The transcriptional repressor
LexA is a key component of the SOS response, the main mechanism for the regulation of …

During colonization and disease, bacterial pathogens must survive the onslaught of the host
immune system. A key component of the innate immune response is the generation of …