The image contrast in magnetic resonance imaging (MRI) is highly sensitive to several
mechanisms that are modulated by the properties of the tissue environment. The degree and …

This review discusses the major contributors to the subtle magnetic properties of brain tissue
and how they affect MRI contrast. With the increased availability of high‐field scanners, the …

During the last five years ultra-high-field magnetic resonance imaging (MRI) has enabled an
unprecedented view of living human brain. Brain tissue contrast in most MRI sequences is …

One objective of modern neuroimaging is to identify markers that can aid in diagnosis,
disease progression monitoring and long-term drug impact analysis. In this study, Parkinson …

Normal ageing is associated with characteristic changes in brain microstructure. Although in
vivo neuroimaging captures spatial and temporal patterns of age-related changes of …

The emergence of multiparametric diffusion models combining diffusion and relaxometry
measurements provides powerful new ways to explore tissue microstructure, with the …

Parkinson's disease is a heterogeneous disorder with both motor and non-motor symptoms
that contribute to functional impairment. To develop effective, disease modifying treatments …

Ultra-high field MRI (≥ 7T) has recently shown great sensitivity to depict patterns of tissue
microarchitecture. Moreover, recent studies have demonstrated a dependency between T2 …

The anisotropy of brain white matter microstructure manifests itself in orientational-
dependence of various MRI contrasts, and can result in significant quantification biases if …

In the present study, we characterized the physiological aging of deep grey matter nuclei by
simultaneously measuring quantitative magnetic resonance parameters sensitive to …