Since the discovery of the first nuclear factor of activated T cells (NFAT) protein more than a
decade ago, the NFAT family of transcription factors has grown to include five members. It …

This review aims to provide an extensive overview of the literature on the clinical
pharmacokinetics of mycophenolate in solid organ transplantation and a briefer summary of …

The calcineurin inhibitor tacrolimus is the backbone of immunosuppressive drug therapy
after solid organ transplantation. Tacrolimus is effective in preventing acute rejection but has …

The roles of nuclear factor of activated T cells (NFAT) transcription factors have been
extensively studied in the immune system. However, ubiquitous expression of NFAT …

Impact of Acute Rejection and New-Onset Diabetes on Long-Ter... : Clinical Journal of the
American Society of Nephrology Impact of Acute Rejection and New-Onset Diabetes on …

Abstract Mycophenolate mofetil (MMF)(CellCept®) is an immunosuppressant drug that is
teratogenic in rats and rabbits. Reports of malformations in 13 offspring of women exposed …

Glucocorticoids are widely used to treat several diseases; however, one of their major
consequences is a deleterious effect on bone that may lead to glucocorticoid-induced …

Everolimus 1.5 or 3 mg/day was compared with mycophenolate mofetil (MMF) 2 g/day in a
randomized, multicenter 36‐month trial in de novo renal allograft recipients (n= 588) …

Type 2 diabetes has traditionally been viewed as a metabolic disorder characterised by
chronic high glucose levels, insulin resistance, and declining insulin secretion from the …

Large between-and within-patient variability has been observed in the pharmacokinetics of
mycophenolic acid (MPA). However, conflicting results exist about the influence of patient …