Epidemiology, risk factors, and prevention of head and neck squamous cell carcinoma

A Barsouk, JS Aluru, P Rawla, K Saginala, A Barsouk - Medical Sciences, 2023 - mdpi.com
Head and neck squamous cell carcinoma (HNSCC) is a group of malignancies, involving
the oral cavity, pharynx, hypopharynx, larynx, nasal cavity, and salivary glands, that together …

Wnt/β-catenin-driven EMT regulation in human cancers

W Xue, L Yang, C Chen, M Ashrafizadeh, Y Tian… - Cellular and Molecular …, 2024 - Springer
Metastasis accounts for 90% of cancer-related deaths among the patients. The
transformation of epithelial cells into mesenchymal cells with molecular alterations can occur …

Cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life years for 29 cancer groups from 2010 to 2019: a systematic analysis …

JM Kocarnik, K Compton, FE Dean, W Fu… - JAMA …, 2022 - jamanetwork.com
Importance The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD
2019) provided systematic estimates of incidence, morbidity, and mortality to inform local …

The inflammatory pathogenesis of colorectal cancer

M Schmitt, FR Greten - Nature Reviews Immunology, 2021 - nature.com
The mutational landscape of colorectal cancer (CRC) does not enable predictions to be
made about the survival of patients or their response to therapy. Instead, studying the …

Hot and cold tumors: Immunological features and the therapeutic strategies

L Wang, H Geng, Y Liu, L Liu, Y Chen, F Wu, Z Liu… - MedComm, 2023 - Wiley Online Library
Abstract The “hotness” or “coldness” of the tumors are determined by the information of the
cancer cells themselves, tumor immune characteristics, tumor microenvironment, and …

Regulated cell death pathways in doxorubicin-induced cardiotoxicity

E Christidi, LR Brunham - Cell Death & Disease, 2021 - nature.com
Doxorubicin is a chemotherapeutic drug used for the treatment of various malignancies;
however, patients can experience cardiotoxic effects and this has limited the use of this …

Mechanisms of cancer metastasis

M Castaneda, P den Hollander, NA Kuburich… - Seminars in cancer …, 2022 - Elsevier
Metastatic cancer is almost always terminal, and more than 90% of cancer deaths result from
metastatic disease. Combating cancer metastasis and post-therapeutic recurrence …

Colorectal cancer statistics, 2020

RL Siegel, KD Miller, A Goding Sauer… - CA: a cancer journal …, 2020 - Wiley Online Library
Colorectal cancer (CRC) is the second most common cause of cancer death in the United
States. Every 3 years, the American Cancer Society provides an update of CRC occurrence …

[PDF][PDF] Adipocyte‐derived exosomal MTTP suppresses ferroptosis and promotes chemoresistance in colorectal cancer

Q Zhang, T Deng, H Zhang, D Zuo, Q Zhu… - Advanced …, 2022 - Wiley Online Library
Obesity is closely related to a poor prognosis in patients with advanced colorectal cancer
(CRC), but the mechanisms remain unclear. Ferroptosis is a form of nonapoptotic cell death …

Medical care costs associated with cancer survivorship in the United States

AB Mariotto, L Enewold, J Zhao, CA Zeruto… - Cancer epidemiology …, 2020 - aacrjournals.org
Background: The prevalence of cancer survivorship is increasing. In this study, we provide
contemporary population–based estimates and projections of the overall and site-specific …