A cargo-sorting DNA robot
INTRODUCTION Since the 1980s, the design and synthesis of molecular machines has
been identified as a grand challenge for molecular engineering. Robots are an important …
been identified as a grand challenge for molecular engineering. Robots are an important …
Fractal assembly of micrometre-scale DNA origami arrays with arbitrary patterns
Self-assembled DNA nanostructures enable nanometre-precise patterning that can be used
to create programmable molecular machines,,,, and arrays of functional materials,,. DNA …
to create programmable molecular machines,,,, and arrays of functional materials,,. DNA …
Pattern generation with nucleic acid chemical reaction networks
Biological and biochemical systems are manifestations of chemical reaction networks
(CRNs). The ability to design and engineer such networks may allow the construction of …
(CRNs). The ability to design and engineer such networks may allow the construction of …
A localized DNA finite-state machine with temporal resolution
The identity and timing of environmental stimulus play a pivotal role in living organisms in
programming their signaling networks and develo** specific phenotypes. The ability to …
programming their signaling networks and develo** specific phenotypes. The ability to …
Compiler-aided systematic construction of large-scale DNA strand displacement circuits using unpurified components
Biochemical circuits made of rationally designed DNA molecules are proofs of concept for
embedding control within complex molecular environments. They hold promise for …
embedding control within complex molecular environments. They hold promise for …
DNA strand-displacement timer circuits
Chemical circuits can coordinate elaborate sequences of events in cells and tissues, from
the self-assembly of biological complexes to the sequence of embryonic development …
the self-assembly of biological complexes to the sequence of embryonic development …
Programming and simulating chemical reaction networks on a surface
Models of well-mixed chemical reaction networks (CRNs) have provided a solid foundation
for the study of programmable molecular systems, but the importance of spatial organization …
for the study of programmable molecular systems, but the importance of spatial organization …
Computing with chemical reaction networks: a tutorial
R Brijder - Natural Computing, 2019 - Springer
Chemical reaction networks (CRNs) model the behavior of chemical reactions in well-mixed
solutions and they can be designed to perform computations. In this tutorial we give an …
solutions and they can be designed to perform computations. In this tutorial we give an …
Mathematical modeling and cellular automata simulation of infectious disease dynamics: Applications to the understanding of herd immunity
The complexity associated with an epidemic defies any quantitatively reliable predictive
theoretical scheme. Here, we pursue a generalized mathematical model and cellular …
theoretical scheme. Here, we pursue a generalized mathematical model and cellular …
Digital nanoreactors to control absolute stoichiometry and spatiotemporal behavior of DNA receptors within lipid bilayers
Interactions between membrane proteins are essential for cell survival but are often poorly
understood. Even the biologically functional ratio of components within a multi-subunit …
understood. Even the biologically functional ratio of components within a multi-subunit …