Molecular probes for autofluorescence-free optical imaging

Y Jiang, K Pu - Chemical reviews, 2021 - ACS Publications
Optical imaging is an indispensable tool in clinical diagnostics and fundamental biomedical
research. Autofluorescence-free optical imaging, which eliminates real-time optical …

Polymeric nanoparticles for drug delivery: Recent developments and future prospects

B Begines, T Ortiz, M Pérez-Aranda, G Martínez… - Nanomaterials, 2020 - mdpi.com
The complexity of some diseases—as well as the inherent toxicity of certain drugs—has led
to an increasing interest in the development and optimization of drug-delivery systems …

In vivo three-dimensional multispectral photoacoustic imaging of dual enzyme-driven cyclic cascade reaction for tumor catalytic therapy

S Lei, J Zhang, NT Blum, M Li, DY Zhang, W Yin… - Nature …, 2022 - nature.com
Non-invasive visualization of dynamic molecular events in real-time via molecular imaging
may enable the monitoring of cascade catalytic reactions in living systems, however effective …

Multifunctional materials for implantable and wearable photonic healthcare devices

GH Lee, H Moon, H Kim, GH Lee, W Kwon… - Nature Reviews …, 2020 - nature.com
Numerous light-based diagnostic and therapeutic devices are routinely used in the clinic.
These devices have a familiar look as items plugged in the wall or placed at patients' …

Recent progress in targeted delivery vectors based on biomimetic nanoparticles

L Chen, W Hong, W Ren, T Xu, Z Qian… - Signal transduction and …, 2021 - nature.com
Over the past decades, great interest has been given to biomimetic nanoparticles (BNPs)
since the rise of targeted drug delivery systems and biomimetic nanotechnology. Biological …

Employment of enhanced permeability and retention effect (EPR): Nanoparticle-based precision tools for targeting of therapeutic and diagnostic agent in cancer

D Kalyane, N Raval, R Maheshwari, V Tambe… - Materials Science and …, 2019 - Elsevier
In tumorous tissues, the absence of vasculature supportive tissues intimates the formation of
leaky vessels and pores (100 nm to 2 μm in diameter) and the poor lymphatic system offers …

Photoacoustic imaging and photothermal therapy of semiconducting polymer nanoparticles: signal amplification and second near‐infrared construction

X Zhen, K Pu, X Jiang - Small, 2021 - Wiley Online Library
Photoacoustic (PA) imaging and photothermal therapy (PTT) have attracted extensive
attention in disease diagnosis and treatment. Although many exogenous contrast agents …

Recent advances of optical imaging in the second near‐infrared window

Kenry, Y Duan, B Liu - Advanced materials, 2018 - Wiley Online Library
The near‐infrared window between 1000 and 1700 nm, commonly termed the “second near‐
infrared (NIR‐II) window,” has quickly emerged as a highly attractive optical region for …

Fluorogenic probes for disease-relevant enzymes

J Zhang, X Chai, XP He, HJ Kim, J Yoon… - Chemical Society …, 2019 - pubs.rsc.org
Traditional biochemical methods for enzyme detection are mainly based on antibody-based
immunoassays, which lack the ability to monitor the spatiotemporal distribution and, in …

Long-lived emissive probes for time-resolved photoluminescence bioimaging and biosensing

KY Zhang, Q Yu, H Wei, S Liu, Q Zhao… - Chemical …, 2018 - ACS Publications
In this Review article, we systematically summarize the design and applications of various
kinds of long-lived emissive probes for bioimaging and biosensing via time-resolved …