[HTML][HTML] Artificial intelligence in drug discovery: what is realistic, what are illusions? Part 1: Ways to make an impact, and why we are not there yet

A Bender, I Cortés-Ciriano - Drug discovery today, 2021 - Elsevier
Highlights•Artificial Intelligence (AI) has transformed many areas such as speech and image
recognition, but not yet drug discovery.•Approaches to AI in drug discovery need to take in …

[PDF][PDF] Balancing accuracy and interpretability of machine learning approaches for radiation treatment outcomes modeling

Y Luo, HH Tseng, S Cui, L Wei, RK Ten Haken… - BJR| Open, 2019 - academic.oup.com
Radiation outcomes prediction (ROP) plays an important role in personalized prescription
and adaptive radiotherapy. A clinical decision may not only depend on an accurate radiation …

Automatic prostate segmentation using deep learning on clinically diverse 3D transrectal ultrasound images

N Orlando, DJ Gillies, I Gyacskov, C Romagnoli… - Medical …, 2020 - Wiley Online Library
Purpose Needle‐based procedures for diagnosing and treating prostate cancer, such as
biopsy and brachytherapy, have incorporated three‐dimensional (3D) transrectal ultrasound …

CT sinogram‐consistency learning for metal‐induced beam hardening correction

HS Park, SM Lee, HP Kim, JK Seo… - Medical physics, 2018 - Wiley Online Library
Purpose This paper proposes a sinogram‐consistency learning method to deal with beam
hardening‐related artifacts in polychromatic computerized tomography (CT). The presence …

Development of a deep learning model to identify lymph node metastasis on magnetic resonance imaging in patients with cervical cancer

Q Wu, S Wang, S Zhang, M Wang, Y Ding… - JAMA network …, 2020 - jamanetwork.com
Importance Accurate identification of lymph node metastasis preoperatively and
noninvasively in patients with cervical cancer can avoid unnecessary surgical intervention …

[HTML][HTML] Automatic segmentation of prostate MRI using convolutional neural networks: Investigating the impact of network architecture on the accuracy of volume …

N Ghavami, Y Hu, E Gibson, E Bonmati… - Medical image …, 2019 - Elsevier
Convolutional neural networks (CNNs) have recently led to significant advances in
automatic segmentations of anatomical structures in medical images, and a wide variety of …

Applications of artificial intelligence in drug design: opportunities and challenges

M Thomas, A Boardman, M Garcia-Ortegon… - Artificial Intelligence in …, 2022 - Springer
Artificial intelligence (AI) has undergone rapid development in recent years and has been
successfully applied to real-world problems such as drug design. In this chapter, we review …

Radiation therapy quality assurance tasks and tools: the many roles of machine learning

AM Kalet, SMH Luk, MH Phillips - Medical physics, 2020 - Wiley Online Library
The recent explosion in machine learning efforts in the quality assurance (QA) space has
produced a variety of proofs‐of‐concept many with promising results. Expected outcomes of …

Spatial descriptions of radiotherapy dose: normal tissue complication models and statistical associations

MA Ebert, S Gulliford, O Acosta… - Physics in Medicine …, 2021 - iopscience.iop.org
For decades, dose-volume information for segmented anatomy has provided the essential
data for correlating radiotherapy dosimetry with treatment-induced complications. Dose …

Artificial intelligence in radiotherapy: a technological review

K Sheng - Frontiers of Medicine, 2020 - Springer
Radiation therapy (RT) is widely used to treat cancer. Technological advances in RT have
occurred in the past 30 years. These advances, such as three-dimensional image guidance …