Heterogeneity and treatment landscape of ovarian carcinoma

AC Veneziani, E Gonzalez-Ochoa, H Alqaisi… - Nature Reviews …, 2023 - nature.com
Ovarian carcinoma is characterized by heterogeneity at the molecular, cellular and
anatomical levels, both spatially and temporally. This heterogeneity affects response to …

[HTML][HTML] Current and emerging methods for ovarian cancer screening and diagnostics: a comprehensive review

JM Liberto, SY Chen, IM Shih, TH Wang, TL Wang… - Cancers, 2022 - mdpi.com
Simple Summary Ovarian high-grade serous carcinoma (HGSC) has a 5-year survival rate
of less than 50%, making it one of the most lethal gynecological cancers for women in the …

Risk reduction and screening of cancer in hereditary breast-ovarian cancer syndromes: ESMO Clinical Practice Guideline☆

C Sessa, J Balmaña, SL Bober… - Annals of …, 2023 - annalsofoncology.org
Hereditary breast and ovarian cancer syndrome (HBOC) is clinically defined by family
history criteria, and molecularly defined by identification of germline pathogenic variants …

Managing menopause after cancer

M Hickey, P Basu, J Sassarini, ME Stegmann… - The Lancet, 2024 - thelancet.com
Globally, 9 million women are diagnosed with cancer each year. Breast cancer is the most
commonly diagnosed cancer worldwide, followed by colorectal cancer in high-income …

Screening and prevention of ovarian cancer

M Sideris, U Menon… - Medical Journal of …, 2024 - Wiley Online Library
Ovarian cancer remains the most lethal gynaecological malignancy with 314 000 cases and
207 000 deaths annually worldwide. Ovarian cancer cases and deaths are predicted to …

BRCA1 and Metastasis: Outcome of Defective DNA Repair

R Krishnan, PS Patel, R Hakem - Cancers, 2021 - mdpi.com
Simple Summary BRCA1 has critical functions in accurately repairing double stand breaks
in the DNA through a process known as homologous recombination. BRCA1 also has …

Gender-specific counselling of patients with upper tract urothelial carcinoma and Lynch syndrome

C Cerrato, SD Pandolfo, R Autorino, A Panunzio… - World Journal of …, 2023 - Springer
Purpose Lynch syndrome (LS) is an autosomal dominant genetic syndrome resulting in a
wide spectrum of malignancies caused by germline mutations in mismatch repair genes …

[HTML][HTML] British Gynaecological Cancer Society (BGCS) ovarian, tubal and primary peritoneal cancer guidelines: Recommendations for practice update 2024

E Moss, A Taylor, A Andreou, C Ang, R Arora… - European Journal of …, 2024 - Elsevier
Recommendations are graded as per the Royal College of Obstetricians and
Gynaecologists document, Clinical Governance Advice No. 1: Guidance for the …

The Psychosocial Impact of the Decision to Undergo Risk-Reducing Sal**o-Oophorectomy Surgery in BRCA Mutation Carriers and the Role of Physician-Patient …

AC Alves-Nogueira, D Melo, C Carona… - Current …, 2023 - mdpi.com
Risk-reducing bilateral sal**o-oophorectomy (RRSO) is an effective prophylactic surgery
provided to premenopausal women carrying BRCA1 or BRCA2 mutations and presenting an …

Risk-reducing sal**ectomy with delayed oophorectomy to prevent ovarian cancer in women with an increased inherited risk: insights into an alternative strategy

TA Gootzen, MP Steenbeek, MHD van Bommel… - Familial Cancer, 2024 - Springer
Epithelial ovarian cancer (EOC) is the most lethal type of gynaecological cancer, due to lack
of effective screening possibilities and because the disease tends to metastasize before …