C–H deuteration of organic compounds and potential drug candidates
C–H deuteration has been intricately developed to satisfy the urgent need for site-selectively
deuterated organic frameworks. Deuteration has been primarily used to study kinetic isotope …
deuterated organic frameworks. Deuteration has been primarily used to study kinetic isotope …
The Suzuki-Miyaura reaction after the Nobel prize
IP Beletskaya, F Alonso, V Tyurin - Coordination Chemistry Reviews, 2019 - Elsevier
Synthetic organic chemistry experienced a significant advance in the last quarter of the 20th
century with the advent of the transition-metal catalyzed cross-coupling reactions. The utility …
century with the advent of the transition-metal catalyzed cross-coupling reactions. The utility …
C–H Functionalization of Pyridines via Oxazino Pyridine Intermediates: Switching to para-Selectivity under Acidic Conditions
para-Selective C–H functionalization of pyridines holds a significant value but remains
underdeveloped. Site-switchable C–H functionalization of pyridines under easily tunable …
underdeveloped. Site-switchable C–H functionalization of pyridines under easily tunable …
Recent advances in metal‐catalyzed functionalization of indoles
K Urbina, D Tresp, K Sipps… - Advanced Synthesis & …, 2021 - Wiley Online Library
Indole is one of the most important heterocycles in organic synthesis, natural products, and
drug discovery. Recently, tremendous advances in the selective functionalization of indoles …
drug discovery. Recently, tremendous advances in the selective functionalization of indoles …
The chemistry of heterocycles in the 21st century
VN Charushin, EV Verbitskiy, ON Chupakhin… - Uspekhi Khimii, 2024 - mathnet.ru
The chemistry of heterocyclic compounds has traditionally been and remains a bright area of
chemical science in Russia. This is due to the fact that many heterocycles find the widest …
chemical science in Russia. This is due to the fact that many heterocycles find the widest …
Benefits and applications of microwave-assisted synthesis of nitrogen containing heterocycles in medicinal chemistry
Nitrogen containing heterocycles are of immense research interest because they are often
found as naturally occurring bioactive compounds. The prominence of N-heterocycles …
found as naturally occurring bioactive compounds. The prominence of N-heterocycles …
Visible-light-induced [3+ 2] cycloadditions of donor/donor diazo intermediates with alkenes to achieve (spiro)-pyrazolines and pyrazoles
Y Zhang, Y Li, SF Ni, JP Li, D **a, X Han, J Lin… - Chemical …, 2023 - pubs.rsc.org
To date,[3+ 2] cycloadditions of diazo esters with alkynes or alkenes have been a robust tool
to generate pyrazoles and pyrazolines. However, methods capable of generating …
to generate pyrazoles and pyrazolines. However, methods capable of generating …
Achmatowicz rearrangement-inspired development of green chemistry, organic methodology, and total synthesis of natural products
L Liang, LD Guo, R Tong - Accounts of Chemical Research, 2022 - ACS Publications
Conspectus The six-membered heterocycles containing oxygen and nitrogen
(tetrahydropyrans, pyrans, piperidines) are among the most common heterocyclic structures …
(tetrahydropyrans, pyrans, piperidines) are among the most common heterocyclic structures …
Molecular editing of pyrroles via a skeletal recasting strategy
Heterocyclic scaffolds are commonly found in numerous biologically active molecules,
therapeutic agents, and agrochemicals. To probe chemical space around heterocycles …
therapeutic agents, and agrochemicals. To probe chemical space around heterocycles …
[HTML][HTML] Recent developments using malononitrile in ultrasound-assisted multicomponent synthesis of heterocycles
Ultrasonic irradiation serves as a vigorous and environmentally sustainable approach for
augmenting multicomponent reactions (MCRs), offering benefits such as thermal …
augmenting multicomponent reactions (MCRs), offering benefits such as thermal …