Biocatalysis harnesses enzymes to make valuable products. This green technology is used
in countless applications from bench scale to industrial production and allows practitioners …

A major goal of evolutionary genetics is to understand the genetic processes that give rise to
phenotypic diversity in multicellular organisms. Alternative splicing generates multiple …

Abstract Background PacBio high fidelity (HiFi) sequencing reads are both long (15–20 kb)
and highly accurate (> Q20). Because of these properties, they have revolutionised genome …

We present YaHS, a user-friendly command-line tool for the construction of chromosome-
scale scaffolds from Hi-C data. It can be run with a single-line command, requires minimal …

Abstract Galaxy (https://galaxyproject. org) is deployed globally, predominantly through free-
to-use services, supporting user-driven research that broadens in scope each year. Users …

Abstract Evaluation of the quality of genomic “data products” such as genome assemblies or
gene sets is of critical importance in order to recognize possible issues and correct them …

Motivation Protein-to-genome alignment is critical to annotating genes in non-model
organisms. While there are a few tools for this purpose, all of them were developed over 10 …

Motivation With the current pace at which reference genomes are being produced, the
availability of tools that can reliably and efficiently generate genome assembly summary …

Abstract Ensembl (https://www. ensembl. org) is unique in its flexible infrastructure for access
to genomic data and annotation. It has been designed to efficiently deliver annotation at …

The Darwin Tree of Life (DToL) project aims to sequence and assemble high-quality
genomes from all eukaryote species in Britain and Ireland, with the first phase of the project …