Recent advances in the microbiological diagnosis of bloodstream infections

W Florio, P Morici, E Ghelardi, S Barnini… - Critical reviews in …, 2018 - Taylor & Francis
Rapid identification (ID) and antimicrobial susceptibility testing (AST) of the causative agent
(s) of bloodstream infections (BSIs) are essential for the prompt administration of an effective …

Oral microbiome and cancer therapy-induced oral mucositis

JLC Mougeot, CB Stevens, DS Morton… - JNCI …, 2019 - academic.oup.com
Abstract Characterization of the role of oral microbiome in cancer therapy-induced oral
mucositis (CTOM) is critical in preventing the clinically deleterious effects on patients' health …

Direct, rapid antimicrobial susceptibility test from positive blood cultures based on microscopic imaging analysis

J Choi, HY Jeong, GY Lee, S Han, S Han, B **… - Scientific reports, 2017 - nature.com
For the timely treatment of patients with infections in bloodstream and cerebrospinal fluid, a
rapid antimicrobial susceptibility test (AST) is urgently needed. Here, we describe a direct …

T2Bacteria magnetic resonance assay for the rapid detection of ESKAPEc pathogens directly in whole blood

G De Angelis, B Posteraro, E De Carolis… - Journal of …, 2018 - academic.oup.com
Objectives To evaluate the magnetic resonance-based T2Bacteria Panel assay for direct
detection of ESKAPEc (Enterococcus faecium, Staphylococcus aureus, Klebsiella …

In vitro Evaluation of BACT/ALERT® VIRTUO®, BACT/ALERT 3D®, and BACTEC™ FX Automated Blood Culture Systems for Detection of Microbial Pathogens Using …

G Menchinelli, FM Liotti, B Fiori, G De Angelis… - Frontiers in …, 2019 - frontiersin.org
Blood culture (BC) is still the standard for diagnosing bloodstream infections (BSIs),
especially those caused by bacteria and fungi. Infection-complicating sepsis or septic shock …

Optimized use of the MALDI BioTyper system and the FilmArray BCID panel for direct identification of microbial pathogens from positive blood cultures

B Fiori, T D'Inzeo, A Giaquinto… - Journal of clinical …, 2016 - journals.asm.org
Despite the current reliance on blood cultures (BCs), the diagnosis of bloodstream infections
(BSIs) can be sped up using new technologies performed directly on positive BC bottles …

Continuous and prolonged intravenous β-lactam dosing: implications for the clinical laboratory

M Grupper, JL Kuti, DP Nicolau - Clinical microbiology reviews, 2016 - journals.asm.org
Beta-lactam antibiotics serve as a cornerstone in the management of bacterial infections
because of their wide spectrum of activity and low toxicity. Since resistance rates among …

A review of novel technologies and techniques associated with identification of bloodstream infection etiologies and rapid antimicrobial genotypic and quantitative …

S Poole, SP Kidd, K Saeed - Expert Review of Molecular …, 2018 - Taylor & Francis
Introduction: The antimicrobial aspect of management of patients with blood stream
infections (BSI) and sepsis is time critical. In an era of increasing antimicrobial resistance …

Anaerobic blood culture positivity at a University Hospital in Hungary: a 5-year comparative retrospective study

M Gajdács, M Ábrók, A Lázár, G Terhes, E Urbán - Anaerobe, 2020 - Elsevier
Anaerobic bacteremia (AB) is usually detected in about 0.5–13% of positive blood cultures.
The aim of this study was to determine prevalence of anaerobic bacteremia over a 5-year …

Comparison of the performance of three blood culture systems in a Chinese tertiary-care hospital

G Li, J Sun, S Pan, W Li, S Zhang, Y Wang… - Frontiers in cellular …, 2019 - frontiersin.org
In this study, we evaluated the performance of three blood culture systems in a Chinese
tertiary-care hospital. Samples of simulated bacteremia were prepared using 10 mL of fresh …