Despite decades of unequivocal evidence that waist circumference provides both
independent and additive information to BMI for predicting morbidity and risk of death, this …

Plant-based diets have become increasingly popular thanks to their purported health
benefits and more recently for their positive environmental impact. Prospective studies …

Chronic caloric restriction (CR) has powerful anticarcinogenic actions in both preclinical and
clinical studies but may be difficult to sustain. As an alternative to CR, there has been …

Calorie restriction (CR) is a dietary intervention with potential benefits for healthspan
improvement and lifespan extension. In 53 (34 CR and 19 control) non-obese adults, we …

Caloric restriction (CR) without malnutrition extends lifespan and delays the onset of age-
related disorders in most species but its impact in nonhuman primates has been …

Increased life expectancy combined with the aging baby boomer generation has resulted in
an unprecedented global expansion of the elderly population. The growing population of …

Calorie restriction (CR), a nutritional intervention of reduced energy intake but with adequate
nutrition, has been shown to extend healthspan and lifespan in rodent and primate models …

The progressive increase in lifespan over the past century carries with it some adversity
related to the accompanying burden of debilitating diseases prevalent in the older …

Summary Protein-restricted (PR), high-carbohydrate diets improve metabolic health in
rodents, yet the precise dietary components that are responsible for these effects have not …

Background Caloric restriction (CR), energy intake reduced below ad libitum (AL) intake,
increases life span in many species. The implications for humans can be clarified by …