Assessing anhedonia in depression: Potentials and pitfalls
The resurgence of interest in anhedonia within major depression has been fuelled by
clinical trials demonstrating its utility in predicting antidepressant response as well as recent …
clinical trials demonstrating its utility in predicting antidepressant response as well as recent …
Activational and effort-related aspects of motivation: neural mechanisms and implications for psychopathology
Motivation has been defined as the process that allows organisms to regulate their internal
and external environment, and control the probability, proximity and availability of stimuli. As …
and external environment, and control the probability, proximity and availability of stimuli. As …
[HTML][HTML] Inhibitory input from the lateral hypothalamus to the ventral tegmental area disinhibits dopamine neurons and promotes behavioral activation
Projections from the lateral hypothalamus (LH) to the ventral tegmental area (VTA),
containing both GABAergic and glutamatergic components, encode conditioned responses …
containing both GABAergic and glutamatergic components, encode conditioned responses …
Effort-based decision-making in major depressive disorder: a translational model of motivational anhedonia.
Anhedonia is a core feature of major depressive disorder (MDD), but the precise nature of
anhedonic symptoms is unknown. Whereas anhedonia has traditionally been viewed as a …
anhedonic symptoms is unknown. Whereas anhedonia has traditionally been viewed as a …
Worth the 'EEfRT'? The effort expenditure for rewards task as an objective measure of motivation and anhedonia
Background Of the putative psychopathological endophenotypes in major depressive
disorder (MDD), the anhedonic subtype is particularly well supported. Anhedonia is …
disorder (MDD), the anhedonic subtype is particularly well supported. Anhedonia is …
Evidence for striatal dopamine release during a video game
Dopaminergic neurotransmission may be involved in learning, reinforcement of behaviour,
attention, and sensorimotor integration,. Binding of the radioligand 11C-labelled raclopride …
attention, and sensorimotor integration,. Binding of the radioligand 11C-labelled raclopride …
The role of nucleus accumbens dopamine in motivated behavior: a unifying interpretation with special reference to reward-seeking
Studies addressing behavioral functions of dopamine (DA) in the nucleus accumbens septi
(NAS) are reviewed. A role of NAS DA in reward has long been suggested. However, some …
(NAS) are reviewed. A role of NAS DA in reward has long been suggested. However, some …
[LLIBRE][B] What's wrong with my mouse?: behavioral phenoty** of transgenic and knockout mice
JN Crawley - 2007 - books.google.com
Dr. Jacqueline N. Crawley, author of the First and Second Editions of What's Wrong with My
Mouse? Behavioral Phenoty** of Transgenic and Knockout Mice, continues to field calls …
Mouse? Behavioral Phenoty** of Transgenic and Knockout Mice, continues to field calls …
Neurobehavioural mechanisms of reward and motivation
The analysis of the behavioural and neural mechanisms of reinforcement and motivation
has benefited from the recent application of learning theory and better anatomical …
has benefited from the recent application of learning theory and better anatomical …
[HTML][HTML] Acute effects of cocaine on human brain activity and emotion
We investigated brain circuitry mediating cocaine-induced euphoria and craving using
functional MRI (fMRI). During double-blind cocaine (0.6 mg/kg) and saline infusions in …
functional MRI (fMRI). During double-blind cocaine (0.6 mg/kg) and saline infusions in …