Improvements in both liquid chromatography (LC) and mass spectrometry (MS)
instrumentation have greatly enhanced proteomic and small molecule metabolomic analysis …

Over the past decades, substantial advances have been made in both the early diagnosis
and accurate prognosis of many cancers because of the impressive development of novel …

With the introduction of recent high‐throughput technologies to various fields of science and
medicine, it is becoming clear that obtaining large amounts of data is no longer a problem in …

Peptidomics is the comprehensive profiling of endogenous peptides from the biological
sources. As with genome, transcriptome, proteome and metabolome, the peptidome is …

The rise of peptides with secondary structures and functions would have been a key step in
the chemical evolution which led to life. As with modern biology, amino acid sequence …

In the past decade, there has been an increasing interest in applying proteomics to assist in
understanding the pathogenesis of ovarian cancer, elucidating the mechanism of drug …

Mass spectrometry-based peptidomic approaches are powerful techniques to detect and
identify the peptide content of biological samples. The present study investigated the …

Purpose For the vast majority of ovarian cancer patients, optimal surgical debulking remains
a key prognostic factor associated with improved survival. A standardized, biomarker‐based …

Protease activity has been associated with pathological processes that can lead to cancer
development and progression. However, understanding the pathological unbalance in …

Currently, evaluation of sperm quality is primarily based on in vitro measures of sperm
function such as motility, viability and/or acrosome reaction. However, results are often …