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High-throughput DNA synthesis for data storage
With the explosion of digital world, the dramatically increasing data volume is expected to
reach 175 ZB (1 ZB= 1012 GB) in 2025. Storing such huge global data would consume tons …
reach 175 ZB (1 ZB= 1012 GB) in 2025. Storing such huge global data would consume tons …
DNA as a universal chemical substrate for computing and data storage
DNA computing and DNA data storage are emerging fields that are unlocking new
possibilities in information technology and diagnostics. These approaches use DNA …
possibilities in information technology and diagnostics. These approaches use DNA …
Symbolic recording of signalling and cis-regulatory element activity to DNA
Measurements of gene expression or signal transduction activity are conventionally
performed using methods that require either the destruction or live imaging of a biological …
performed using methods that require either the destruction or live imaging of a biological …
Engineering wired life: synthetic biology for electroactive bacteria
Electroactive bacteria produce or consume electrical current by moving electrons to and
from extracellular acceptors and donors. This specialized process, known as extracellular …
from extracellular acceptors and donors. This specialized process, known as extracellular …
A designer synthetic chromosome fragment functions in moss
LG Chen, T Lan, S Zhang, M Zhao, G Luo, Y Gao… - Nature Plants, 2024 - nature.com
Rapid advances in DNA synthesis techniques have enabled the assembly and engineering
of viral and microbial genomes, presenting new opportunities for synthetic genomics in …
of viral and microbial genomes, presenting new opportunities for synthetic genomics in …
Information-theoretic foundations of DNA data storage
Due to its longevity and enormous information density, DNA is an attractive medium for
archival data storage. Natural DNA more than 700.000 years old has been recovered, and …
archival data storage. Natural DNA more than 700.000 years old has been recovered, and …
Transcriptional recording by CRISPR spacer acquisition from RNA
The ability to record transcriptional events within a cell over time would help to elucidate
how molecular events give rise to complex cellular behaviours and states. However, current …
how molecular events give rise to complex cellular behaviours and states. However, current …
Programming mammalian cell behaviors by physical cues
In recent decades, the field of synthetic biology has witnessed remarkable progress, driving
advances in both research and practical applications. One pivotal area of development …
advances in both research and practical applications. One pivotal area of development …
Recording gene expression order in DNA by CRISPR addition of retron barcodes
Biological processes depend on the differential expression of genes over time, but methods
to make physical recordings of these processes are limited. Here we report a molecular …
to make physical recordings of these processes are limited. Here we report a molecular …
A DNA circuit that records molecular events
Characterizing the relative onset time, strength, and duration of molecular signals is critical
for understanding the operation of signal transduction and genetic regulatory networks …
for understanding the operation of signal transduction and genetic regulatory networks …