Short-chain fatty-acid-producing bacteria: key components of the human gut microbiota

W Fusco, MB Lorenzo, M Cintoni, S Porcari… - Nutrients, 2023 - mdpi.com
Short-chain fatty acids (SCFAs) play a key role in health and disease, as they regulate gut
homeostasis and their deficiency is involved in the pathogenesis of several disorders …

The role of short-chain fatty acids in immunity, inflammation and metabolism

Y Yao, X Cai, W Fei, Y Ye, M Zhao… - Critical reviews in food …, 2022 - Taylor & Francis
Short-chain fatty acids (SCFAs) are carboxylic acids with carbon atom numbers less than 6,
which are important metabolites of gut microbiome. Existing research shows that SCFAs …

[HTML][HTML] Gut microbiota in hypertension and atherosclerosis: a review

BJH Verhaar, A Prodan, M Nieuwdorp, M Muller - Nutrients, 2020 - mdpi.com
Gut microbiota and its metabolites such as short chain fatty acids (SCFA),
lipopolysaccharides (LPS), and trimethylamine-N-oxide (TMAO) impact cardiovascular …

[HTML][HTML] Butyrate: a double-edged sword for health?

H Liu, J Wang, T He, S Becker, G Zhang, D Li, X Ma - Advances in nutrition, 2018 - Elsevier
Butyrate, a four-carbon short-chain fatty acid, is produced through microbial fermentation of
dietary fibers in the lower intestinal tract. Endogenous butyrate production, delivery, and …

Beneficial effect of the short-chain fatty acid propionate on vascular calcification through intestinal microbiota remodelling

J Yan, Y Pan, W Shao, C Wang, R Wang, Y He… - Microbiome, 2022 - Springer
Background Vascular calcification is a major cause of the high morbidity and mortality of
cardiovascular diseases and is closely associated with the intestinal microbiota. Short-chain …

[HTML][HTML] Pro-and anti-inflammatory effects of short chain fatty acids on immune and endothelial cells

M Li, BCAM Van Esch, GTM Wagenaar… - European journal of …, 2018 - Elsevier
In the gastro-intestinal tract, short chain fatty acids (SCFAs) have protective effects on
epithelial cells. However, their effects on inflammatory cytokine production by endothelial …

Role of the intestinal microbiome and its therapeutic intervention in cardiovascular disorder

A Luqman, A Hassan, M Ullah, S Naseem… - Frontiers in …, 2024 - frontiersin.org
The gut microbiome is a heterogeneous population of microbes comprising viruses,
bacteria, fungi, and protozoa. Such a microbiome is essential for sustaining host equilibrium …

[HTML][HTML] Short-chain fatty acids, maternal microbiota and metabolism in pregnancy

M Ziętek, Z Celewicz, M Szczuko - Nutrients, 2021 - mdpi.com
Short-chain fatty acids (SCFAs), as products of intestinal bacterial metabolism, are
particularly relevant in the diagnosis of intestinal dysbiosis. The most common studies of …

[HTML][HTML] The impact of microbiota-derived short-chain fatty acids on macrophage activities in disease: Mechanisms and therapeutic potentials

H Duan, LJ Wang, M Huangfu, H Li - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Short-chain fatty acids (SCFAs) derived from the fermentation of carbohydrates by gut
microbiota play a crucial role in regulating host physiology. Among them, acetate …

A proinflammatory gut microbiota increases systemic inflammation and accelerates atherosclerosis

E Brandsma, NJ Kloosterhuis, M Koster… - Circulation …, 2019 - ahajournals.org
Rationale: Several studies have suggested a role for the gut microbiota in inflammation and
atherogenesis. A causal relation relationship between gut microbiota, inflammation, and …