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In situ label-free X-ray imaging for visualizing the localization of nanomedicines and subcellular architecture in intact single cells
M Cao, Y Wang, L Wang, K Zhang, Y Guan, Y Guo… - Nature …, 2024 - nature.com
Understanding the intracellular behaviors of nanomedicines and morphology variation of
subcellular architecture impacted by nanomaterial–biology (nano–bio) interactions could …
subcellular architecture impacted by nanomaterial–biology (nano–bio) interactions could …
Nitrogen-fixing organelle in a marine alga
Symbiotic interactions were key to the evolution of chloroplast and mitochondria organelles,
which mediate carbon and energy metabolism in eukaryotes. Biological nitrogen fixation, the …
which mediate carbon and energy metabolism in eukaryotes. Biological nitrogen fixation, the …
Soft X‐ray tomograms provide a structural basis for whole‐cell modeling
Develo** in silico models that accurately reflect a whole, functional cell is an ongoing
challenge in biology. Current efforts bring together mathematical models, probabilistic …
challenge in biology. Current efforts bring together mathematical models, probabilistic …
Using soft X-ray tomography for rapid whole-cell quantitative imaging of SARS-CoV-2-infected cells
High-resolution and rapid imaging of host cell ultrastructure can generate insights toward
viral disease mechanism, for example for a severe acute respiratory syndrome coronavirus …
viral disease mechanism, for example for a severe acute respiratory syndrome coronavirus …
Soft X-ray tomography to map and quantify organelle interactions at the mesoscale
Inter-organelle interactions are a vital part of normal cellular function; however, these have
proven difficult to quantify due to the range of scales encountered in cell biology and the …
proven difficult to quantify due to the range of scales encountered in cell biology and the …
Three-dimensional label-free observing of the self-assembled nanoparticles inside a single cell at nanoscale resolution
H Zhou, Y Guo, T Fu, Y Peng, Z Chen, Y Cui, M Guo… - ACS …, 2024 - ACS Publications
Understanding the intracellular behavior of nanoparticles (NPs) plays a key role in
optimizing the self-assembly performance of nanomedicine. However, conducting the 3D …
optimizing the self-assembly performance of nanomedicine. However, conducting the 3D …
Bayesian metamodeling of complex biological systems across varying representations
Comprehensive modeling of a whole cell requires an integration of vast amounts of
information on various aspects of the cell and its parts. To divide and conquer this task, we …
information on various aspects of the cell and its parts. To divide and conquer this task, we …
Insulator-based dielectrophoresis-assisted separation of insulin secretory vesicles
Organelle heterogeneity and inter-organelle contacts within a single cell contribute to the
limited sensitivity of current organelle separation techniques, thus hindering organelle …
limited sensitivity of current organelle separation techniques, thus hindering organelle …
Reagents and models for detecting endogenous GLP1R and GIPR
Abstract Glucagon-like peptide-1 receptor (GLP1R) agonists target the GLP1R, whereas
dual GLP1R/gastric inhibitory polypeptide receptor (GIPR) agonists target both the GLP1R …
dual GLP1R/gastric inhibitory polypeptide receptor (GIPR) agonists target both the GLP1R …
Advanced light source analytical techniques for exploring the biological behavior and fate of nanomedicines
M Cao, K Zhang, S Zhang, Y Wang… - ACS Central Science, 2022 - ACS Publications
Exploration of the biological behavior and fate of nanoparticles, as affected by the
nanomaterial–biology (nano–bio) interaction, has become progressively critical for guiding …
nanomaterial–biology (nano–bio) interaction, has become progressively critical for guiding …