Neuronal nicotinic acetylcholine receptors

J Lindstrom - Ion channels, 1996 - Springer
Studies of the structure and function of neuronal nicotinic acetylcholine receptors (AChRs)
evolved out of studies of muscle AChRs. This review will begin with a brief summary of …

Heteromeric α7β2 nicotinic acetylcholine receptors in the brain

J Wu, Q Liu, P Tang, JD Mikkelsen, J Shen… - Trends in …, 2016 - cell.com
The α7 nicotinic acetylcholine receptor (α7 nAChR) is highly expressed in the brain, where it
maintains various neuronal functions including (but not limited to) learning and memory. In …

Immunocytochemical localization of the α7 subunit of the nicotinic acetylcholine receptor in the rat central nervous system

ED del Toro, JM Juiz, X Peng… - Journal of …, 1994 - Wiley Online Library
Previous molecular cloning studies have revealed that α‐bungarotoxin binding proteins
present in the brain are members of the neuronal nicotinic acetylcholine receptor gene …

Human alpha 7 acetylcholine receptor: cloning of the alpha 7 subunit from the SH-SY5Y cell line and determination of pharmacological properties of native receptors …

X Peng, M Katz, V Gerzanich… - Molecular …, 1994 - molpharm.aspetjournals.org
The alpha-bungarotoxin-binding acetylcholine receptors from the human neuroblastoma cell
line SH-SY5Y were found to cross-react with some monoclonal antibodies to alpha 7 …

[HTML][HTML] Discoveries and future significance of research into amyloid-beta/α7-containing nicotinic acetylcholine receptor (nAChR) interactions

P Whiteaker, AA George - Pharmacological research, 2023 - Elsevier
Initiated by findings that Alzheimer's disease is associated with a profound loss of
cholinergic markers in human brain, decades of studies have examined the interactions …

[PDF][PDF] Homomers of alpha 8 and alpha 7 subunits of nicotinic receptors exhibit similar channel but contrasting binding site properties.

V Gerzanich, R Anand, J Lindstrom - Molecular Pharmacology, 1994 - Citeseer
SUMMARY a8 subunits of a-bungarotoxin-sensitive chick neuronal nicotinic acetyicholine
receptors expressed in Xenopus oocytes from cRNA are shown to form homomenc …

[HTML][HTML] Nicotine'actions on energy balance: Friend or foe?

P Seoane-Collazo, C Diéguez, R Nogueiras… - Pharmacology & …, 2021 - Elsevier
Obesity has reached pandemic proportions and is associated with severe comorbidities,
such as type 2 diabetes mellitus, hepatic and cardiovascular diseases, and certain cancer …

Neuromuscular blocking drugs do not alter the pupillary light reflex of anesthetized humans

AT Gray, ST Krejci, MD Larson - Archives of neurology, 1997 - jamanetwork.com
Objective: To test the hypothesis that systemically administered neuromuscular blocking
drugs acutely alter resting pupil size or the direct reflex response to light in anesthetized …

Is modulation of nicotinic acetylcholine receptors by melatonin relevant for therapy with cholinergic drugs?

RP Markus, CLM Silva, DG Franco… - Pharmacology & …, 2010 - Elsevier
Melatonin, the darkness hormone, synchronizes several physiological functions to light/dark
cycle. Besides the awake/sleep cycle that is intuitively linked to day/night, daily variations in …

[HTML][HTML] Functional contribution of the α7 subunit to multiple subtypes of nicotinic receptors in embryonic chick sympathetic neurones

CR Yu, LW Role - The Journal of physiology, 1998 - ncbi.nlm.nih.gov
Many studies of the α7 subunit of the neuronal nicotinic acetylcholine receptor (nAChR)
family have demonstrated that this α-bungarotoxin (α-BgTx)-binding neuronal receptor can …