Transaminases (TAs) are one of the most promising biocatalysts in organic synthesis for the
preparation of chiral amino compounds. The concise reaction, excellent enantioselectivity …

In this review we analyse structure/sequence–function relationships for the superfamily of
PLP-dependent enzymes with special emphasis on class III transaminases. Amine …

Highlights•Discovery: novel biocatalytic strategies for amine synthesis.•Exploration:
expanding the scope towards challenging substrates.•Maturation: optimizing biocatalysis for …

A one-pot chemoenzymatic sequential cascade for the synthesis of chiral amines from
alkynes was developed. In this integrated approach, just ppm amounts of gold catalysts …

Although the amine transaminase from Vibrio fluvialis has often been applied as a catalyst
for the biocatalytic preparation of various chiral primary amines, it is not suitable for the …