The modern pharmacology of paracetamol: therapeutic actions, mechanism of action, metabolism, toxicity and recent pharmacological findings
Paracetamol is used worldwide for its analgesic and antipyretic actions. It has a spectrum of
action similar to that of NSAIDs and resembles particularly the COX-2 selective inhibitors …
action similar to that of NSAIDs and resembles particularly the COX-2 selective inhibitors …
Cannabinoid receptors: An update on cell signaling, pathophysiological roles and therapeutic opportunities in neurological, cardiovascular, and inflammatory …
The identification of the human cannabinoid receptors and their roles in health and disease,
has been one of the most significant biochemical and pharmacological advancements to …
has been one of the most significant biochemical and pharmacological advancements to …
[HTML][HTML] Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia
Cannabidiol is a component of marijuana that does not activate cannabinoid receptors, but
moderately inhibits the degradation of the endocannabinoid anandamide. We previously …
moderately inhibits the degradation of the endocannabinoid anandamide. We previously …
The molecular logic of endocannabinoid signalling
D Piomelli - Nature Reviews Neuroscience, 2003 - nature.com
The endocannabinoids are a family of lipid messengers that engage the cell surface
receptors that are targeted by Δ9-tetrahydrocannabinol, the active principle in marijuana …
receptors that are targeted by Δ9-tetrahydrocannabinol, the active principle in marijuana …
Brain monoglyceride lipase participating in endocannabinoid inactivation
TP Dinh, D Carpenter, FM Leslie… - Proceedings of the …, 2002 - National Acad Sciences
The endogenous cannabinoids (endocannabinoids) are lipid molecules that may mediate
retrograde signaling at central synapses and other forms of short-range neuronal …
retrograde signaling at central synapses and other forms of short-range neuronal …
[HTML][HTML] Role of endogenous cannabinoids in synaptic signaling
Freund, Tamás F., István Katona, and Daniele Piomelli. Role of Endogenous Cannabinoids
in Synaptic Signaling. Physiol Rev 83: 1017–1066, 2003; 10.1152/physrev. 00004.2003 …
in Synaptic Signaling. Physiol Rev 83: 1017–1066, 2003; 10.1152/physrev. 00004.2003 …
[LIVRE][B] Pharmacological actions of cannabinoids
RG Pertwee - 2005 - Springer
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SpringerLink Account Menu Find a journal Publish with us Track your research Search Cart …
SpringerLink Account Menu Find a journal Publish with us Track your research Search Cart …
The biological control of voluntary exercise, spontaneous physical activity and daily energy expenditure in relation to obesity: human and rodent perspectives
Mammals expend energy in many ways, including basic cellular maintenance and repair,
digestion, thermoregulation, locomotion, growth and reproduction. These processes can …
digestion, thermoregulation, locomotion, growth and reproduction. These processes can …
Cannabinoid receptors and their ligands
RG Pertwee, RA Ross - … , Leukotrienes and Essential Fatty Acids (PLEFA), 2002 - Elsevier
There are at least two types of cannabinoid receptors, CB1 and CB2, both coupled to G
proteins. CB1 receptors exist primarily on central and peripheral neurons, one of their …
proteins. CB1 receptors exist primarily on central and peripheral neurons, one of their …
Cerebrospinal anandamide levels are elevated in acute schizophrenia and are inversely correlated with psychotic symptoms
A Giuffrida, FM Leweke, CW Gerth… - …, 2004 - nature.com
The endocannabinoids are a family of bioactive lipids that activate CB 1 cannabinoid
receptors in the brain and exert intense emotional and cognitive effects. Here, we have …
receptors in the brain and exert intense emotional and cognitive effects. Here, we have …