Offering the latest information in magnetic nanoparticle (MNP) research, Magnetic
Nanoparticles: From Fabrication to Clinical Applications provides a comprehensive review …

RNA interference (RNAi) has been very successfully applied as a gene-silencing technology
in both plants and invertebrates, but many practical obstacles need to be overcome before it …

Small interfering RNAs (siRNAs) are a new class of promising therapeutic molecules that
can be used for sequence-specific downregulation of disease-causing genes. However …

Genome-wide genetic approaches have proven useful for examining pathways of biological
significance in model organisms such as Saccharomyces cerevisiae, Drosophila …

Bone homeostasis requires a delicate balance between the activities of bone-resorbing
osteoclasts and bone-forming osteoblasts. Various molecules coordinate osteoclast function …

Toll-like receptors (TLRs) sense infection by detecting molecular structures of microbial
origin. TLR3, TLR7 and TLR9 recognize nucleic acids and are localized to intracellular …

Scaffolded DNA origami, a method to create self-assembled nanostructures with spatially
addressable features, has recently been used to develop water-soluble molecular chips for …

Osteoclasts are specialized macrophages that resorb bone. Mice lacking the AP-1
component c-Fos are osteopetrotic because of a lack of osteoclast differentiation and show …

ABSTRACT RNA interference has emerged as a powerful technique to downregulate the
expression of specific genes in cells and in animals, thus opening new perspectives in fields …

This work introduces a novel chitosan-based siRNA nanoparticle delivery system for RNA
interference in vitro and in vivo. The formation of interpolyelectrolyte complexes between …