The M editerranean diet and consumption of olive oil have been connected in several
studies with longevity and a reduced risk of morbidity and mortality. Lifestyle, such as regular …

Aldosterone, secreted by the adrenal zona glomerulosa, enhances sodium retention, thus
increasing blood volume and pressure. Excessive production of aldosterone results in high …

Differentiation of mesenchymal stem cells into a particular lineage is tightly regulated, and
malfunction of this regulation could lead to pathological consequences. Patients with …

Runx1 is highly expressed in osteoblasts, however, its function in osteogenesis is unclear.
We generated mesenchymal progenitor-specific (Runx1 f/f Twist2-Cre) and osteoblast …

Abstract Context: Adipokines (leptin, adiponectin, resistin, visfatin) and ghrelin may be
implicated in bone metabolism. Objective: The aim was to perform an overview of the …

Purpose: To investigate vertebral bone marrow fat content in elderly subjects related to sex,
age, and bone mineral density (BMD) and relate these findings to published data in younger …

Obesity has been associated with high bone mineral density (BMD) but a greater propensity
to fracture. Some obese individuals have increased marrow adipose tissue (MAT), but the …

Incidence of skeletal metastases and death from prostate cancer greatly increases with age
and obesity, conditions which increase marrow adiposity. Bone marrow adipocytes are …

Primary osteoporosis is an age-related disease characterized by an imbalance in bone
homeostasis. While the resorptive aspect of the disease has been studied intensely, less is …

Osteoporosis, the most common chronic metabolic bone disease, is characterized by low
bone mass and increased bone fragility. Nowadays more than 200 million individuals are …