Highly pathogenic avian influenza viruses at the wild–domestic bird interface in Europe: future directions for research and surveillance
Highly pathogenic avian influenza (HPAI) outbreaks in wild birds and poultry are no longer a
rare phenomenon in Europe. In the past 15 years, HPAI outbreaks—in particular those …
rare phenomenon in Europe. In the past 15 years, HPAI outbreaks—in particular those …
Quadrivalent influenza nanoparticle vaccines induce broad protection
S Boyoglu-Barnum, D Ellis, RA Gillespie… - Nature, 2021 - nature.com
Influenza vaccines that confer broad and durable protection against diverse viral strains
would have a major effect on global health, as they would lessen the need for annual …
would have a major effect on global health, as they would lessen the need for annual …
Emergence and spread of novel H5N8, H5N5 and H5N1 clade 2.3. 4.4 highly pathogenic avian influenza in 2020
Analyses of HPAI H5 viruses from poultry outbreaks across a wide Eurasian region since
July 2020 including the Russian Federation, Republics of Iraq and Kazakhstan, and recent …
July 2020 including the Russian Federation, Republics of Iraq and Kazakhstan, and recent …
Selective packaging of the influenza A genome and consequences for genetic reassortment
M Gerber, C Isel, V Moules, R Marquet - Trends in microbiology, 2014 - cell.com
Influenza A viruses package their segmented RNA genome in a selective manner. Electron
tomography, biochemical assays, and replication assays of viruses produced by reverse …
tomography, biochemical assays, and replication assays of viruses produced by reverse …
Programmable antivirals targeting critical conserved viral RNA secondary structures from influenza A virus and SARS-CoV-2
RJ Hagey, M Elazar, EA Pham, S Tian, L Ben-Avi… - Nature medicine, 2022 - nature.com
Influenza A virus's (IAV's) frequent genetic changes challenge vaccine strategies and
engender resistance to current drugs. We sought to identify conserved and essential RNA …
engender resistance to current drugs. We sought to identify conserved and essential RNA …
Colocalization of different influenza viral RNA segments in the cytoplasm before viral budding as shown by single-molecule sensitivity FISH analysis
The Influenza A virus genome consists of eight negative sense, single-stranded RNA
segments. Although it has been established that most virus particles contain a single copy of …
segments. Although it has been established that most virus particles contain a single copy of …
Packaging signal of influenza A virus
X Li, M Gu, Q Zheng, R Gao, X Liu - Virology Journal, 2021 - Springer
Influenza A virus (IAV) contains a genome with eight single-stranded, negative-sense RNA
segments that encode 17 proteins. During its assembly, all eight separate viral RNA (vRNA) …
segments that encode 17 proteins. During its assembly, all eight separate viral RNA (vRNA) …
A functional sequence-specific interaction between influenza A virus genomic RNA segments
C Gavazzi, M Yver, C Isel, RP Smyth… - Proceedings of the …, 2013 - National Acad Sciences
Influenza A viruses cause annual influenza epidemics and occasional severe pandemics.
Their genome is segmented into eight fragments, which offers evolutionary advantages but …
Their genome is segmented into eight fragments, which offers evolutionary advantages but …
In Vivo Bioluminescent Imaging of Influenza A Virus Infection and Characterization of Novel Cross-Protective Monoclonal Antibodies
Influenza A virus is a major human pathogen responsible for seasonal epidemics as well as
pandemic outbreaks. Due to the continuing burden on human health, the need for new tools …
pandemic outbreaks. Due to the continuing burden on human health, the need for new tools …
Transport of the influenza virus genome from nucleus to nucleus
The segmented genome of an influenza virus is encapsidated into ribonucleoprotein
complexes (RNPs). Unusually among RNA viruses, influenza viruses replicate in the …
complexes (RNPs). Unusually among RNA viruses, influenza viruses replicate in the …