[HTML][HTML] NRF2 and NF-қB interplay in cerebrovascular and neurodegenerative disorders: molecular mechanisms and possible therapeutic approaches
Electrophiles and reactive oxygen species (ROS) play a major role in modulating cellular
defense mechanisms as well as physiological functions, and intracellular signaling …
defense mechanisms as well as physiological functions, and intracellular signaling …
Animal models of traumatic brain injury and assessment of injury severity
Traumatic brain injury (TBI) contributes a major cause of death, disability, and mental health
disorders. Most TBI patients suffer long-term post-traumatic stress disorder, cognitive …
disorders. Most TBI patients suffer long-term post-traumatic stress disorder, cognitive …
[HTML][HTML] Intranasally administered human MSC-derived extracellular vesicles inhibit NLRP3-p38/MAPK signaling after TBI and prevent chronic brain dysfunction
Traumatic brain injury (TBI) leads to lasting brain dysfunction with chronic
neuroinflammation typified by nucleotide-binding domain leucine-rich repeat and pyrin …
neuroinflammation typified by nucleotide-binding domain leucine-rich repeat and pyrin …
GABAkines–Advances in the discovery, development, and commercialization of positive allosteric modulators of GABAA receptors
Positive allosteric modulators of γ-aminobutyric acid-A (GABA A) receptors or GABAkines
have been widely used medicines for over 70 years for anxiety, epilepsy, sleep, and other …
have been widely used medicines for over 70 years for anxiety, epilepsy, sleep, and other …
The complexity of neuroinflammation consequent to traumatic brain injury: from research evidence to potential treatments
This review recounts the definitions and research evidence supporting the multifaceted roles
of neuroinflammation in the injured brain following trauma. We summarise the literature …
of neuroinflammation in the injured brain following trauma. We summarise the literature …
Sex differences in the epilepsies and associated comorbidities: implications for use and development of pharmacotherapies
The epilepsies are common neurologic disorders characterized by spontaneous recurrent
seizures. Boys, girls, men, and women of all ages are affected by epilepsy and, in many …
seizures. Boys, girls, men, and women of all ages are affected by epilepsy and, in many …
Measuring anxiety-like behaviors in rodent models of traumatic brain injury
Anxiety is a common complaint following acquired traumatic brain injury (TBI). However, the
measurement of dysfunctional anxiety behavioral states following experimental TBI in …
measurement of dysfunctional anxiety behavioral states following experimental TBI in …
Psychedelics for acquired brain injury: a review of molecular mechanisms and therapeutic potential
Acquired brain injury (ABI), such as traumatic brain injury and stroke, is a leading cause of
disability worldwide, resulting in debilitating acute and chronic symptoms, as well as an …
disability worldwide, resulting in debilitating acute and chronic symptoms, as well as an …
Traumatic brain injury and blood–brain barrier (BBB): underlying pathophysiological mechanisms and the influence of cigarette smoking as a premorbid condition
Traumatic brain injury (TBI) is among the most pressing global health issues and prevalent
causes of cerebrovascular and neurological disorders all over the world. In addition to the …
causes of cerebrovascular and neurological disorders all over the world. In addition to the …
Incidence and risk factors of posttraumatic epilepsy following pediatric traumatic brain injury: A systematic review and meta‐analysis
Posttraumatic epilepsy (PTE) is a well‐known chronic complication following traumatic brain
injury (TBI). Despite some evidence that age at the time of injury may influence the likelihood …
injury (TBI). Despite some evidence that age at the time of injury may influence the likelihood …