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Current understanding of the human microbiome
Our understanding of the link between the human microbiome and disease, including
obesity, inflammatory bowel disease, arthritis and autism, is rapidly expanding …
obesity, inflammatory bowel disease, arthritis and autism, is rapidly expanding …
The progress of gut microbiome research related to brain disorders
There is increasing evidence showing that the dynamic changes in the gut microbiota can
alter brain physiology and behavior. Cognition was originally thought to be regulated only by …
alter brain physiology and behavior. Cognition was originally thought to be regulated only by …
Shotgun metagenomics, from sampling to analysis
Diverse microbial communities of bacteria, archaea, viruses and single-celled eukaryotes
have crucial roles in the environment and in human health. However, microbes are …
have crucial roles in the environment and in human health. However, microbes are …
Characterization of the gut microbiome using 16S or shotgun metagenomics
The advent of next generation sequencing (NGS) has enabled investigations of the gut
microbiome with unprecedented resolution and throughput. This has stimulated the …
microbiome with unprecedented resolution and throughput. This has stimulated the …
Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences
Profiling phylogenetic marker genes, such as the 16S rRNA gene, is a key tool for studies of
microbial communities but does not provide direct evidence of a community's functional …
microbial communities but does not provide direct evidence of a community's functional …
[HTML][HTML] Monitoring antibiotic resistance genes in wastewater environments: the challenges of filling a gap in the One-Health cycle
Antibiotic resistance (AR) is a global problem requiring international cooperation and
coordinated action. Global monitoring must rely on methods available and comparable …
coordinated action. Global monitoring must rely on methods available and comparable …
phyloseq: an R package for reproducible interactive analysis and graphics of microbiome census data
Background The analysis of microbial communities through DNA sequencing brings many
challenges: the integration of different types of data with methods from ecology, genetics …
challenges: the integration of different types of data with methods from ecology, genetics …
The ecologist's field guide to sequence‐based identification of biodiversity
The past 100 years of ecological research has seen substantial progress in understanding
the natural world and likely effects of change, whether natural or anthropogenic. Traditional …
the natural world and likely effects of change, whether natural or anthropogenic. Traditional …
[HTML][HTML] Conducting a microbiome study
Human microbiome research is an actively develo** area of inquiry, with ramifications for
our lifestyles, our interactions with microbes, and how we treat disease. Advances depend …
our lifestyles, our interactions with microbes, and how we treat disease. Advances depend …
Cross-biome metagenomic analyses of soil microbial communities and their functional attributes
For centuries ecologists have studied how the diversity and functional traits of plant and
animal communities vary across biomes. In contrast, we have only just begun exploring …
animal communities vary across biomes. In contrast, we have only just begun exploring …