Deciphering cell–cell interactions and communication from gene expression
Cell–cell interactions orchestrate organismal development, homeostasis and single-cell
functions. When cells do not properly interact or improperly decode molecular messages …
functions. When cells do not properly interact or improperly decode molecular messages …
Vascular endothelial cell development and diversity
Vascular endothelial cells form the inner layer of blood vessels where they have a key role
in the development and maintenance of the functional circulatory system and provide …
in the development and maintenance of the functional circulatory system and provide …
Robust map** of spatiotemporal trajectories and cell–cell interactions in healthy and diseased tissues
Spatial transcriptomics (ST) technologies generate multiple data types from biological
samples, namely gene expression, physical distance between data points, and/or tissue …
samples, namely gene expression, physical distance between data points, and/or tissue …
Influenza virus and SARS-CoV-2: pathogenesis and host responses in the respiratory tract
T Flerlage, DF Boyd, V Meliopoulos… - Nature Reviews …, 2021 - nature.com
Influenza viruses cause annual epidemics and occasional pandemics of respiratory tract
infections that produce a wide spectrum of clinical disease severity in humans. The novel …
infections that produce a wide spectrum of clinical disease severity in humans. The novel …
Capillary cell-type specialization in the alveolus
In the mammalian lung, an apparently homogenous mesh of capillary vessels surrounds
each alveolus, forming the vast respiratory surface across which oxygen transfers to the …
each alveolus, forming the vast respiratory surface across which oxygen transfers to the …
Integrated single-cell atlas of endothelial cells of the human lung
Background: Cellular diversity of the lung endothelium has not been systematically
characterized in humans. We provide a reference atlas of human lung endothelial cells …
characterized in humans. We provide a reference atlas of human lung endothelial cells …
The cellular and physiological basis for lung repair and regeneration: past, present, and future
The respiratory system, which includes the trachea, airways, and distal alveoli, is a complex
multi-cellular organ that intimately links with the cardiovascular system to accomplish gas …
multi-cellular organ that intimately links with the cardiovascular system to accomplish gas …
Vascular endothelial cells: heterogeneity and targeting approaches
Forming the inner layer of the vascular system, endothelial cells (ECs) facilitate a multitude
of crucial physiological processes throughout the body. Vascular ECs enable the vessel wall …
of crucial physiological processes throughout the body. Vascular ECs enable the vessel wall …
Endothelial AHR activity prevents lung barrier disruption in viral infection
Disruption of the lung endothelial–epithelial cell barrier following respiratory virus infection
causes cell and fluid accumulation in the air spaces and compromises vital gas exchange …
causes cell and fluid accumulation in the air spaces and compromises vital gas exchange …
[HTML][HTML] Differential roles of regulatory T cells in acute respiratory infections
M Jovisic, N Mambetsariev, BD Singer… - The Journal of …, 2023 - Am Soc Clin Investig
JCI - Differential roles of regulatory T cells in acute respiratory infections Go to JCI Insight About
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