The role of vitamin D in reducing cancer risk and progression

D Feldman, AV Krishnan, S Swami… - Nature reviews …, 2014 - nature.com
Vitamin D is not really a vitamin but the precursor to the potent steroid hormone calcitriol,
which has widespread actions throughout the body. Calcitriol regulates numerous cellular …

Association between vitamin D supplementation and mortality: systematic review and meta-analysis

Y Zhang, F Fang, J Tang, L Jia, Y Feng, P Xu… - bmj, 2019 - bmj.com
Objective To investigate whether vitamin D supplementation is associated with lower
mortality in adults. Design Systematic review and meta-analysis of randomised controlled …

[HTML][HTML] Vitamin D supplements and prevention of cancer and cardiovascular disease

JAE Manson, NR Cook, IM Lee… - … England Journal of …, 2019 - Mass Medical Soc
Background It is unclear whether supplementation with vitamin D reduces the risk of cancer
or cardiovascular disease, and data from randomized trials are limited. Methods We …

Vitamin D and mortality: meta-analysis of individual participant data from a large consortium of cohort studies from Europe and the United States

B Schöttker, R Jorde, A Peasey, B Thorand… - Bmj, 2014 - bmj.com
Objective To investigate the association between serum 25-hydroxyvitamin D concentrations
(25 (OH) D) and mortality in a large consortium of cohort studies paying particular attention …

Association of body weight with response to vitamin D supplementation and metabolism

DK Tobias, H Luttmann-Gibson, S Mora… - JAMA Network …, 2023 - jamanetwork.com
Importance In the Vitamin D and Omega-3 Trial (VITAL), the effects of randomized vitamin D
supplementation (cholecalciferol), 2000 IU/d, reduced the risk of several health outcomes …

[HTML][HTML] Vitamin D and multiple health outcomes: an umbrella review of observational studies, randomized controlled trials, and Mendelian randomization studies

D Liu, X Meng, Q Tian, W Cao, X Fan, L Wu, M Song… - Advances in …, 2022 - Elsevier
Observational studies, randomized controlled trials (RCTs), and Mendelian randomization
(MR) studies have yielded inconsistent results on the associations of vitamin D …

Non-musculoskeletal benefits of vitamin D

SJ Wimalawansa - The Journal of steroid biochemistry and molecular …, 2018 - Elsevier
The aim of this study is to determine and critically evaluate the plausible relationships of
vitamin D with extra-skeletal tissues in humans. Severe vitamin D deficiency results in rickets …

Principal results of the VITamin D and OmegA-3 TriaL (VITAL) and updated meta-analyses of relevant vitamin D trials

JAE Manson, SS Bassuk, JE Buring… - The Journal of steroid …, 2020 - Elsevier
Whether supplemental vitamin D reduces risk of cancer or cardiovascular disease (CVD) is
relatively unexplored in randomized trial settings. The VITamin D and OmegA-3 TriaL …

Vitamin D and cancer risk and mortality: state of the science, gaps, and challenges

AM Mondul, SJ Weinstein, TM Layne… - Epidemiologic …, 2017 - academic.oup.com
There has been substantial enthusiasm recently regarding the potential role of vitamin D in
the primary and secondary prevention of cancer. Laboratory studies demonstrate a range of …

Vitamin D supplementation for prevention of cancer in adults

G Bjelakovic, LL Gluud, D Nikolova… - Cochrane Database …, 2014 - cochranelibrary.com
Vitamin D supplementation for prevention of cancer in adults - Bjelakovic, G - 2014 | Cochrane
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