Low back pain (LBP), a prevalent and costly disease around the world, is predominantly
caused by intervertebral disc (IVD) degeneration (IDD). LBP also presents a substantial …

Lumbar disc degeneration is one of the leading causes of chronic low back pain. The
degenerative cascade is often initiated by an imbalance between catabolic and anabolic …

Exosome therapy is a promising therapeutic approach for intervertebral disc degeneration
(IVDD) and achieves its therapeutic effects by regulating metabolic disorders, the …

Description: The American College of Physicians (ACP) developed this guideline to present
the evidence and provide clinical recommendations on noninvasive treatment of low back …

Introduction Low back pain (LBP) is a common health problem, and the leading cause of
activity limitation and work absence among people of all ages and socioeconomic strata …

Intervertebral disc (IVD) degeneration is a major cause of low back pain, a prevalent and
chronic condition that has a striking effect on quality of life. Currently, no approved …

Chronic low back pain (CLBP) is a chronic pain syndrome in the lower back region, lasting
for at least 3 months. CLBP represents the second leading cause of disability worldwide …

The editorial briefs about the issues of the Journal Annals of Neurology. The authors provide
a summary overview of the substantial current and future economic impact of neurological …

Low back pain (LBP) is a major reason for disability, and symptomatic intervertebral disc
(IVD) degeneration (IDD) contributes to roughly 40% of all LBP cases. Current treatment …

Biomarkers are biological characteristics that can be used to indicate health or disease. This
paper reviews studies on biomarkers of low back pain (LBP) in human subjects. LBP is the …