The current guideline represents the 6th edition of the “Japanese Clinical Practice Guideline
for Diabetes” which has been revised every three years since its first appearance in 2004 to …

Metabolomics is an emerging field that quantifies numerous metabolites systematically. The
key purpose of metabolomics is to identify the metabolites corresponding to each biological …

Objective To systematically review associations between intake of saturated fat and trans
unsaturated fat and all cause mortality, cardiovascular disease (CVD) and associated …

High-throughput targeted lipid profiling with liquid chromatography-mass spectrometry (LC-
MS) has been used extensively to identify associations between plasma lipid species and …

Excessive accumulation of lipids can lead to lipotoxicity, cell dysfunction and alteration in
metabolic pathways, both in adipose tissue and peripheral organs, like liver, heart, pancreas …

Type 2 diabetes mellitus (T2DM) is associated with increased total plasma free fatty acid
(FFA) concentrations and an elevated risk of cardiovascular disease. The exact mechanisms …

Background Conflicting evidence exists regarding the association between saturated fatty
acids (SFAs) and type 2 diabetes. In this longitudinal case-cohort study, we aimed to …

The role of C17: 0 and C15: 0 in human health has recently been reinforced following a
number of important biological and nutritional observations. Historically, odd chain saturated …

The effects of both the amount and quality of dietary fat have been studied intensively during
the past decades. Previously, low-fat diets were recommended without much attention to the …

Purpose To comprehensively review the data on the relationship between the consumption
of dairy fat and high-fat dairy foods, obesity, and cardiometabolic disease. Methods We have …