Ferroptosis is a mechanism of regulated necrotic cell death characterized by iron-
dependent, lipid peroxidation-driven membrane destruction that can be inhibited by …

The sulfur biochemistry of the thiol group endows cysteines with a number of highly
specialized and unique features that enable them to serve a variety of different functions in …

Reactive oxygen species (ROS)–the byproducts of aerobic metabolism–influence numerous
aspects of the plant life cycle and environmental response mechanisms. In plants, ROS act …

Cysteine is one of the least abundant amino acids, yet it is frequently found as a highly
conserved residue within functional (regulatory, catalytic, or binding) sites in proteins. It is …

Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …

Summary Low-molecular-weight (LMW) thiols are small-molecule antioxidants required for
the maintenance of intracellular redox homeostasis. However, many host-associated …

Multidrug resistance (MDR) is a major obstacle to successful cancer therapy, especially for
chemotherapy. The new drug delivery system (DDS) provides promising approaches to …

Significance: Mitochondrial glutathione fulfills crucial roles in a number of processes,
including iron–sulfur cluster biosynthesis and peroxide detoxification. Recent Advances …

S-glutathionylation, the post-translational modification forming mixed disulfides between
protein reactive thiols and glutathione, regulates redox-based signaling events in the cell …

Reactive oxygen species (ROS), including the superoxide radical anion (O 2•–), hydrogen
peroxide (H 2 O 2), and the hydroxyl radical (• HO), are inherent components of bacterial …