ADP-ribosylation is a ubiquitous modification of biomolecules, including proteins and
nucleic acids, that regulates various cellular functions in all kingdoms of life. The recent …

Posttranslational modifications (PTMs) regulate protein functions and interactions. ADP-
ribosylation is a PTM, in which ADP-ribosyltransferases use nicotinamide adenine …

ADP-ribosylation (ADPr) is a posttranslational modification (PTM) of proteins that controls
many cellular processes, including DNA repair, transcription, chromatin regulation and …

Although protein ADP-ribosylation is involved in diverse biological processes, it has
remained a challenge to identify ADP-ribose acceptor sites. Here, we present an …

ADP-ribosylation is an intricate and versatile posttranslational modification involved in the
regulation of a vast variety of cellular processes in all kingdoms of life. Its complexity derives …

Sirtuins are NAD+-dependent enzymes universally present in all organisms, where they play
central roles in regulating numerous biological processes. Although early studies showed …

Recent developments indicate that macrodomains, an ancient and diverse protein domain
family, are key players in the recognition, interpretation, and turnover of ADP-ribose (ADPr) …

Acetylation is a posttranslational modification conserved in all domains of life that is carried
out by N-acetyltransferases. While acetylation can occur on N α-amino groups, this review …

Adenosine diphosphate (ADP)‐ribosylation is a chemical modification of macromolecules
that plays an important role in regulation of quintessential biological processes such as DNA …

Rapid response to environmental changes is achieved by uni‐and multicellular organisms
through a series of molecular events, often involving modification of macromolecules …