Designing a multi-epitope vaccine to provoke the robust immune response against influenza A H7N9
A new strain of Influenza A Virus (IAV), so-called" H7N9 Avian Influenza", is the first strain of
this virus in which a human is infected by transmitting the N9 of influenza virus. Although …
this virus in which a human is infected by transmitting the N9 of influenza virus. Although …
Human neutralizing antibodies target a conserved lateral patch on H7N9 hemagglutinin head
Avian influenza A virus H7N9 causes severe human infections with> 30% fatality. Currently,
there is no H7N9-specific prevention or treatment for humans. Here, from a 2013 H7N9 …
there is no H7N9-specific prevention or treatment for humans. Here, from a 2013 H7N9 …
Host genes and influenza pathogenesis in humans: an emerging paradigm
Highlights•Host genes play an important role in the pathogenesis of influenza virus
infection.•High-throughput technologies accelerate the discovery of susceptibility …
infection.•High-throughput technologies accelerate the discovery of susceptibility …
Mycophenolic acid, an immunomodulator, has potent and broad-spectrum in vitro antiviral activity against pandemic, seasonal and avian influenza viruses affecting …
KKW To, KY Mok, ASF Chan… - Journal of General …, 2016 - microbiologyresearch.org
Immunomodulators have been shown to improve the outcome of severe pneumonia. We
have previously shown that mycophenolic acid (MPA), an immunomodulator, has antiviral …
have previously shown that mycophenolic acid (MPA), an immunomodulator, has antiviral …
Co-stimulation with TLR7 agonist imiquimod and inactivated influenza virus particles promotes mouse B cell activation, differentiation, and accelerated antigen …
Current influenza vaccines have relatively low effectiveness, especially against antigenically
drifted strains, the effectiveness is even lower in the elderly and immunosuppressed …
drifted strains, the effectiveness is even lower in the elderly and immunosuppressed …
Development of an adjuvanted nanoparticle vaccine against influenza virus, an in vitro study
K Rungrojcharoenkit, P Sunintaboon, D Ellison… - PLoS …, 2020 - journals.plos.org
Influenza is an infectious respiratory illness caused by influenza viruses. Despite yearly
updates, the efficacy of influenza vaccines is significantly curtailed by the virus antigenic drift …
updates, the efficacy of influenza vaccines is significantly curtailed by the virus antigenic drift …
Avian influenza virus A H7N9 infects multiple mononuclear cell types in peripheral blood and induces dysregulated cytokine responses and apoptosis in infected …
Most patients with avian influenza A H7N9 virus (H7N9) infection suffer from severe illness,
accompanied by dysregulated cytokine/chemokine response, delayed viral clearance and …
accompanied by dysregulated cytokine/chemokine response, delayed viral clearance and …
Peritoneal cells mediate immune responses and cross-protection against influenza A virus
Intraperitoneal inoculation with live influenza A virus confers protection against intranasal
infections in mice and ferrets. However, the responses of peritoneal cells to influenza A virus …
infections in mice and ferrets. However, the responses of peritoneal cells to influenza A virus …
Antibody immunity induced by H7N9 avian influenza vaccines: Evaluation criteria, affecting factors, and implications for rational vaccine design
Z Hu, X Jiao, X Liu - Frontiers in Microbiology, 2017 - frontiersin.org
Severe H7N9 avian influenza virus (AIV) infections in humans have public health authorities
around the world on high alert for the potential development of a human influenza …
around the world on high alert for the potential development of a human influenza …
Evaluation of the adjuvant effect of imiquimod and CpG ODN 1826 in chimeric DNA vaccine against Japanese encephalitis
X Zang, G Li, J Zhu, X Dong, Y Zhai - International Immunopharmacology, 2024 - Elsevier
Vaccines represent a significant milestone in the history of human medical science and
serve as the primary means for controlling infectious diseases. In recent years, the …
serve as the primary means for controlling infectious diseases. In recent years, the …