Peptide-based supramolecular systems chemistry seeks to mimic the ability of life forms to
use conserved sets of building blocks and chemical reactions to achieve a bewildering array …

Cyclodipeptides (CDPs) or 2, 5-diketopiperazines (DKPs) can exert a variety of biological
activities and display pronounced resistance against enzymatic hydrolysis as well as a …

Nature chose phosphates to activate amino acids, where reactive intermediates and
complex machinery drive the construction of polyamides. Outside of biology, the pathways …

Amino acid stereoconfiguration has been shown to play a key role in the self-assembly of
unprotected tripeptides into hydrogels under physiological conditions. Dramatic changes …

Light-triggered drug release from hydrogels is a promising method to improve efficiency of
antitumor treatment, as an alternative to existing photodynamic therapies. Here we report a …

Molecular self-assembly is a widespread natural phenomenon and has inspired several
researchers to synthesize a compendium of nano/microstructures with widespread …

There is an increasing interest towards the development of new antimicrobial coatings,
especially in light of the emergence of antimicrobial resistance (AMR) towards common …

Heating of linear dipeptides above a critical temperature initiates their cyclization even in the
solid state. This method of obtaining cyclic dipeptides meets the requirements of “green …

An economical, solvent-free, and metal-free method for peptide synthesis via C–N bond
cleavage using lactams has been developed. The method not only eliminates the need for …

Cyclodipeptides (CDPs) are distinct chemical scaffolds that show a wide range of
bioactivities pertinent to medicine, agriculture, chemical catalysis, and material sciences …