As a major component of the human body, the extracellular matrix (ECM) is a complex
biopolymer network. The ECM not only hosts a plethora of biochemical interactions but also …

The native extracellular matrix (ECM) generally exhibits dynamic mechanical properties and
displays time‐dependent responses to deformation or mechanical loading, in terms of …

The efficacy of adoptive T-cell therapies largely depends on the generation of T-cell
populations that provide rapid effector function and long-term protective immunity. Yet it is …

In tissues, many cells are surrounded by and interact with a three-dimensional soft
extracellular matrix (ECM). Both the physical and biochemical properties of the ECM play a …

The extracellular matrix (ECM) performs many critical functions, one of which is to provide
structural and mechanical integrity, and many of the constituent proteins have clear …

Brillouin microscopy is a technique for mechanical characterization of biological material
without contact at high three-dimensional resolution. Here, we introduce dual line-scanning …

Quantifying the mechanical response of the biological milieu (such as the cell's interior) and
complex fluids (such as biomolecular condensates) would enable a better understanding of …

Background: Tumorigenesis is attributed to the interactions of cancer cells with the tumor
microenvironment through both biochemical cues and physical stimuli. Increased matrix …

Cellular and tissue biosystems emerge from the assembly of their constituent molecules and
obtain a set of specific material properties. To measure these properties and understand …

Microrheology encompasses a range of methods to measure the mechanical properties of
soft materials. By characterizing the motion of embedded microscopic particles …