The science and engineering behind sensitized brain-controlled bionic hands

C Pandarinath, SJ Bensmaia - Physiological Reviews, 2022 - journals.physiology.org
Advances in our understanding of brain function, along with the development of neural
interfaces that allow for the monitoring and activation of neurons, have paved the way for …

Brain computer interfaces in rehabilitation medicine

MA Bockbrader, G Francisco, R Lee, J Olson… - PM&R, 2018 - Elsevier
One innovation currently influencing physical medicine and rehabilitation is brain–computer
interface (BCI) technology. BCI systems used for motor control record neural activity …

Perception of microstimulation frequency in human somatosensory cortex

CL Hughes, SN Flesher, JM Weiss, M Boninger… - Elife, 2021 - elifesciences.org
Microstimulation in the somatosensory cortex can evoke artificial tactile percepts and can be
incorporated into bidirectional brain–computer interfaces (BCIs) to restore function after …

Intracortical somatosensory stimulation to elicit fingertip sensations in an individual with spinal cord injury

MS Fifer, DP McMullen, LE Osborn, TM Thomas… - Neurology, 2022 - neurology.org
Background and Objectives The restoration of touch to fingers and fingertips is critical to
achieving dexterous neuroprosthetic control for individuals with sensorimotor dysfunction …

Biomimetic multi-channel microstimulation of somatosensory cortex conveys high resolution force feedback for bionic hands

CM Greenspon, G Valle, TG Hobbs, C Verbaarschot… - Biorxiv, 2023 - pmc.ncbi.nlm.nih.gov
Manual interactions with objects are supported by tactile signals from the hand. This tactile
feedback can be restored in brain-controlled bionic hands via intracortical microstimulation …

Evoking stable and precise tactile sensations via multi-electrode intracortical microstimulation of the somatosensory cortex

CM Greenspon, G Valle, ND Shelchkova… - Nature Biomedical …, 2024 - nature.com
Tactile feedback from brain-controlled bionic hands can be partially restored via intracortical
microstimulation (ICMS) of the primary somatosensory cortex. In ICMS, the location of …

Behavioral assessment of sensitivity to intracortical microstimulation of primate somatosensory cortex

S Kim, T Callier, GA Tabot, RA Gaunt… - Proceedings of the …, 2015 - pnas.org
Intracortical microstimulation (ICMS) is a powerful tool to investigate the functional role of
neural circuits and may provide a means to restore sensation for patients for whom …

Engineering artificial somatosensation through cortical stimulation in humans

B Lee, D Kramer, M Armenta Salas, S Kellis… - Frontiers in systems …, 2018 - frontiersin.org
Sensory feedback is a critical aspect of motor control rehabilitation following paralysis or
amputation. Current human studies have demonstrated the ability to deliver some of this …

Dynamic amplitude modulation of microstimulation evokes biomimetic onset and offset transients and reduces depression of evoked calcium responses in sensory …

C Hughes, T Kozai - Brain stimulation, 2023 - Elsevier
Background Intracortical microstimulation (ICMS) is an emerging approach to restore
sensation to people with neurological injury or disease. Biomimetic microstimulation, or …

Bidirectional brain-computer interfaces

C Hughes, A Herrera, R Gaunt, J Collinger - Handbook of clinical neurology, 2020 - Elsevier
Brain-computer interfaces (BCIs) are devices that interface with the brain to enable
interaction with the environment. BCIs have the potential to improve the quality of life for …