When Szent-Györgyi called water the “matrix of life”, 1 he was echoing an old sentiment.
Paracelsus in the 16th century said that “water was the matrix of the world and of all its …

This review describes selected basics of water in biomolecular recognition. We focus on a
qualitative understanding of the most important physical aspects, how these change in …

Hydration water is the natural matrix of biological macromolecules and is essential for their
activity in cells. The coupling between water and protein dynamics has been intensively …

The dynamics of proteins in solution includes a variety of processes, such as backbone and
side-chain fluctuations, interdomain motions, as well as global rotational and translational …

Abstract Information regarding a lecture on the development of multiscale models for
complex chemical systems from H+ H< sub> 2</sub> to biomolecules is presented. The …

Magic-angle spinning solid-state NMR (SSNMR) studies of the β1 immunoglobulin binding
domain of protein G (GB1) are presented. Chemical shift correlation spectra at 11.7 T (500 …

The recent revolution in cryo electron microscopy (cryo-EM) allows the determination of
structures of macromolecular complexes at atomic resolution. Cryo-EM also provides …

Terahertz time domain spectroscopy shows that the protein dynamical transition, the rapid
increase in protein dynamics occurring at∼ 200 K, needs neither tertiary nor secondary …

This work reviews the strip** off, role of water molecules in activity, and flexibility of
immobilized Candida antarctica lipase B (CALB). Employment of CALB in ring opening …

Microbes utilize enzymes to perform a variety of functions. Enzymes are biocatalysts working
as highly efficient machines at the molecular level. In the past, enzymes have been viewed …