Objectives This review provided a conceptual framework of sample size calculations in the
studies of diagnostic test accuracy in various conditions and test outcomes. Methods The …

Efficient access to chemical information contained in scientific literature, patents, technical
reports, or the web is a pressing need shared by researchers and patent attorneys from …

Background Conducting a systematic review demands a significant amount of effort in
screening titles and abstracts. To accelerate this process, various tools that utilize active …

Receiver operating characteristic (ROC) curves are frequently used in biomedical
informatics research to evaluate classification and prediction models for decision support …

Background Systematic reviews address a specific clinical question by unbiasedly
assessing and analyzing the pertinent literature. Citation screening is a time-consuming and …

Objective: To determine whether automated classification of document citations can be
useful in reducing the time spent by experts reviewing journal articles for inclusion in …

Background Although many aspects of systematic reviews use computational tools,
systematic reviewers have been reluctant to adopt machine learning tools. Discussion We …

Background We investigate the accuracy of different similarity approaches for clustering over
two million biomedical documents. Clustering large sets of text documents is important for a …

Objective Evidence-based medicine (EBM) is a decision-making process based on the
conscious and judicious use of the best available scientific evidence. However, the …

Medical systematic reviews answer particular questions within a very specific domain of
expertise by selecting and analysing the current pertinent literature. As part of this process …