The gut virome: A new microbiome component in health and disease

Z Cao, N Sugimura, E Burgermeister, MP Ebert… - …, 2022 - thelancet.com
The human gastrointestinal tract harbours an abundance of viruses, collectively known as
the gut virome. The gut virome is highly heterogeneous across populations and is linked to …

The human virome: viral metagenomics, relations with human diseases, and therapeutic applications

GH Bai, SC Lin, YH Hsu, SY Chen - Viruses, 2022 - mdpi.com
The human body is colonized by a wide range of microorganisms. The field of viromics has
expanded since the first reports on the detection of viruses via metagenomic sequencing in …

Genome binning of viral entities from bulk metagenomics data

J Johansen, DR Plichta, JN Nissen… - Nature …, 2022 - nature.com
Despite the accelerating number of uncultivated virus sequences discovered in
metagenomics and their apparent importance for health and disease, the human gut virome …

The role of tissue-resident macrophages in the development and treatment of inflammatory bowel disease

S Ma, J Zhang, H Liu, S Li, Q Wang - Frontiers in cell and …, 2022 - frontiersin.org
Inflammatory bowel disease (IBD), comprising Crohn's disease and ulcerative colitis, is a
refractory disease with many immune abnormalities and pathologies in the gastrointestinal …

Alteration of the gut microbiome in inflammatory bowel disease

A Andoh, A Nishida - Digestion, 2023 - karger.com
Background: Alteration of the gut microbial structure and function (dysbiosis) is associated
with the pathogenesis of various disorders including inflammatory bowel disease (IBD) …

Role of bacteriophages in sha** gut microbial community

MR Mahmud, SK Tamanna, S Akter, L Mazumder… - Gut …, 2024 - Taylor & Francis
Phages are the most diversified and dominant members of the gut virobiota. They play a
crucial role in sha** the structure and function of the gut microbial community and …

Phage therapy in gastrointestinal diseases

B Gutiérrez, P Domingo-Calap - Microorganisms, 2020 - mdpi.com
Gastrointestinal tract microbiota plays a key role in the regulation of the pathogenesis of
several gastrointestinal diseases. In particular, the viral fraction, composed essentially of …

Roles of gut bacteriophages in the pathogenesis and treatment of inflammatory bowel disease

L Qv, S Mao, Y Li, J Zhang, L Li - Frontiers in cellular and infection …, 2021 - frontiersin.org
Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, are
chronic, relapsing intestinal inflammatory disorders. Although the molecular mechanisms …

Looking into the future of phage-based control of zoonotic pathogens in food and animal production

M Gambino, L Brøndsted - Current Opinion in Biotechnology, 2021 - Elsevier
Highlights•Phages are promising solutions to control zoonotic pathogens in animals and
food.•Data must be collected from the laboratory to the farms and the food industry.•Complex …

Metagenomic analysis of primary colorectal carcinomas and their metastases identifies potential microbial risk factors

L Marongiu, JJM Landry, T Rausch… - Molecular …, 2021 - Wiley Online Library
The paucity of microbiome studies at intestinal tissues has contributed to a yet limited
understanding of potential viral and bacterial cofactors of colorectal cancer (CRC) …