When a calorie is not just a calorie: Diet quality and timing as mediators of metabolism and healthy aging

MM Mihaylova, A Chaix, M Delibegovic, JJ Ramsey… - Cell metabolism, 2023 - cell.com
An epidemic of obesity has affected large portions of the world, increasing the risk of
develo** many different age-associated diseases, including cancer, cardiovascular …

Dietary regulation in health and disease

Q Wu, ZJ Gao, X Yu, P Wang - Signal Transduction and Targeted …, 2022 - nature.com
Nutriments have been deemed to impact all physiopathologic processes. Recent evidences
in molecular medicine and clinical trials have demonstrated that adequate nutrition …

Lifelong restriction of dietary branched-chain amino acids has sex-specific benefits for frailty and life span in mice

NE Richardson, EN Konon, HS Schuster, AT Mitchell… - Nature Aging, 2021 - nature.com
Protein-restricted diets promote health and longevity in many species. While the precise
components of a protein-restricted diet that mediate the beneficial effects to longevity have …

Dietary factors and their influence on immunotherapy strategies in oncology: a comprehensive review

A Golonko, T Pienkowski, R Swislocka… - Cell Death & …, 2024 - nature.com
Immunotherapy is emerging as a promising avenue in oncology, gaining increasing
importance and offering substantial advantages when compared to chemotherapy or …

[HTML][HTML] The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice

SM Solon-Biet, AC McMahon, JWO Ballard… - Cell metabolism, 2014 - cell.com
The fundamental questions of what represents a macronutritionally balanced diet and how
this maintains health and longevity remain unanswered. Here, the Geometric Framework, a …

Dietary restriction and lifespan: Lessons from invertebrate models

P Kapahi, M Kaeberlein, M Hansen - Ageing research reviews, 2017 - Elsevier
Dietary restriction (DR) is the most robust environmental manipulation known to increase
active and healthy lifespan in many species. Despite differences in the protocols and the …

[HTML][HTML] Commensal bacteria and essential amino acids control food choice behavior and reproduction

R Leitão-Gonçalves, Z Carvalho-Santos… - PLoS …, 2017 - journals.plos.org
Choosing the right nutrients to consume is essential to health and wellbeing across species.
However, the factors that influence these decisions are poorly understood. This is …

[HTML][HTML] Drosophila as a model for ageing

MDW Piper, L Partridge - Biochimica et Biophysica Acta (BBA)-Molecular …, 2018 - Elsevier
Drosophila melanogaster has been a key model in develo** our current understanding of
the molecular mechanisms of ageing. Of particular note is its role in establishing the …

Dietary interventions and precision nutrition in cancer therapy

C Martínez-Garay, N Djouder - Trends in Molecular Medicine, 2023 - cell.com
In recent years dietary interventions have become a promising tool in cancer treatment and
have demonstrated a powerful ability to alter metabolism and tumor growth, development …

[BOK][B] The evolution of parental care

NJ Royle, PT Smiseth, M Kölliker - 2012 - books.google.com
Parental care is a trait that shows tremendous diversity both within and across different
animal taxa, and is an important topic in evolutionary biology and behavioural ecology …