Occurrence and fate of antidepressants in the aquatic environment: Insights into toxicological effects on the aquatic life, analytical methods, and removal techniques

A Singh, D Saidulu, AK Gupta, V Kubsad - Journal of Environmental …, 2022 - Elsevier
The consumption of antidepressants has increased on a global scale. These medications
are frequently prescribed to treat mental health-related disorders and their usage is …

The traditional use of native Brazilian plants for male sexual dysfunction: Evidence from ethnomedicinal applications, animal models, and possible mechanisms of …

TM Teixeira, DD Boeff, L de Oliveira Carvalho… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Sexual dysfunction is a multifactorial health condition
characterized by distressing disturbances in the sexual response and libido, leading to an …

Exposure to amitriptyline induces persistent gut damages and dysbiosis of the gut microbiota in zebrafish (Danio rerio)

Y Shi, C Chen, X Wu, Z Han, S Zhang, K Chen… - … and Physiology Part C …, 2022 - Elsevier
Amitriptyline (AMI), the most commonly prescribed tricyclic antidepressant, is widely
detected in water environments. Exposure to AMI may lead to diverse adverse effects on …

Ameliorative anti-coagulant, anti-oxidative and anti-ferroptotic activities of nanocurcumin and donepezil on coagulation, oxidation and ferroptosis in Alzheimer's …

NF Nawar, DM Beltagy, TM Mohamed… - Toxicology …, 2024 - academic.oup.com
Alzheimer's disease (ad) is a neurological condition that worsens over time and is
characterized by the buildup of amyloid (Aβ) plaques in the brain parenchyma …

Ameliorative role of chitosan nanoparticles against silver nanoparticle-induced reproductive toxicity in male albino rats

AAE Mahgoob, E Tousson, MA Abd Eldaim… - … Science and Pollution …, 2023 - Springer
This study was designed to evaluate the protective potentials of chitosan nanoparticles
(ChNPs) against silver nanoparticle (AgNP)-induced reproductive toxicity in male Wister …

[HTML][HTML] Role of oral supplementation of damiana (Turnera diffusa) reduces the renal toxicity, apoptosis and DNA damage associated with amitriptyline administration …

AF Hasan, HM Hameed, E Tousson… - Biomedical and …, 2022 - biomedpharmajournal.org
Major depressive disorder and anxiety disorders are two mental diseases that are treated
with amitriptyline (AMT). AMT treatments induced liver, heart and testes toxicity; As a result …

Impact of Saussurea lappa root extract against copper oxide nanoparticles induced oxidative stress and toxicity in rat cardiac tissues

E Tousson, DM El‐Gharbawy - Environmental Toxicology, 2023 - Wiley Online Library
Abstract Copper oxide nanoparticles (CuO NPs) have developed as a significant class of
nanomaterial with potential dangers to organisms and the environment in a variety of …

Arbutin abrogates testicular ischemia/reperfusion injury in rats through repression of inflammation and ER stress

EA Demir, S Demir, IO Kazaz, H Kucuk, NT Alemdar… - Tissue and Cell, 2023 - Elsevier
The aim of this study was to investigate the effects of arbutin (ARB) administration on
oxidative stress, inflammation, endoplasmic reticulum (ER) stress and apoptosis in an …

Chlorogenic acid co‐administration abates tamoxifen‐mediated reproductive toxicities in male rats: an experimental approach

SE Owumi, RA Anaikor, UO Arunsi… - Journal of Food …, 2021 - Wiley Online Library
Reports over the years have demonstrated toxic side effect–including reproductive toxicity‐
of tamoxifen (TAM), a drug of choice in the management of primary breast cancer …

Oral administration of Turnera diffusa willd. ex Schult. extract ameliorates steroidogenesis and spermatogenesis impairment in the testes of rats with type-2 diabetes …

GG Kumar, EK Kilari, G Nelli, NB Salleh - Journal of Ethnopharmacology, 2023 - Elsevier
Abstract Ethnopharmacological relevance Turnera diffusa Willd. ex Schult.(T. diffusa) has
traditionally been used to treat male reproductive dysfunction and have aphrodisiac …